摘要
在抗击严重急性呼吸综合征(SARS)、中东呼吸综合征(MERS)和新型冠状病毒感染(COVID-19)过程中,国内外利用草药减轻患者病证,降低感染人数,并丰富相关机制。该文综述了公开报道的可能有或初步证明有临床防疫效果的71个科157种草药,包括甘草等传统中药。这些草药的抗病毒机制包括抑制病毒生活周期、减缓感染后血液细胞因子水平的暴涨和后续器官的损伤等,部分草药还可通过改善环境湿度和释放挥发性成分起到防疫的作用。旨在总结相关防疫经验和机制,为更好理解传统中草药的抗病毒效果提供资料,彰显中医的价值,并为应对疫情后状态和未来可能的呼吸道病毒感染提供经验。
During the fights against SARS,MERF and COVID-19,herbal medicine has been utilized domestically and internationally to alleviate symptoms,reduce infection rates,and enrich our understanding of relevant mechanisms.This review summarizes publicly reported 157 herbals of 71 families including traditional Chinese medicine like licorice that demonstrate potential clinical preventive effects.The antiviral mechanisms of these herbals include the inhibition of viral life cycles,alleviation of the surge of blood cell cytokines and subsequent organ damage,and some herbals can also act as preventive agents by improving environmental humidity and releasing volatile components.The purpose of this study is to summarize relevant preventive experiences and mechanisms,provide evidence for a better understanding of the antiviral effects of traditional herbal medicine,demonstrate the great value of traditional Chinese medicine and accumulate experience to prepare for the post-epidemic status and potential future similar respiratory virus infections.
作者
张仲鸣
贺子懿
郭笑园
王娟
ZHANG Zhongming;HE Ziyi;GUO Xiaoyuan;WANG Juan(ZHANG Zhongjing College of Chinese Medicine,Nanyang Institute of Technology,Nanyang 473003,Henan,China)
出处
《辽宁中医药大学学报》
CAS
2024年第6期1-10,共10页
Journal of Liaoning University of Traditional Chinese Medicine
基金
河南省自然科学基金项目(242300421302)
河南省医学教育研究项目(Wjlx20211110)。
关键词
冠状病毒
草药
抗病毒机制
细胞因子
coronavirus
herbal medicine
anti-viral mechanisms
cytokines
