期刊文献+

2887例老年骨质疏松性脊柱压缩性骨折流行病学特点分析

Epidemiological analysis of 2887 elderly patients with osteoporotic spinal compression fractures
下载PDF
导出
摘要 目的:分析老年骨质疏松性脊柱压缩性骨折住院患者的流行病学特征及治疗等情况,为疾病防治提供数据支持。方法:选取徐州市中心医院2010年1月—2020年8月2887例老年骨质疏松性脊柱压缩性骨折住院患者为研究对象。收集所有患者的年龄、性别、治疗方式、住院费用、住院日、是否发生二次骨折住院、合并疾病等信息,分析疾病的性别、年龄特征、骨折椎体分布、抗骨质疏松治疗率的年度变化特点。结果:各年龄段女性患者均多于男性,差异有统计学意义(P<0.05)。男性患者中,70~79岁年龄段病例数最多;女性患者中,60~69岁年龄段病例数最多。2887例住院患者共3637个椎体发生骨折,患者骨折椎体数量大致呈单峰分布,胸腰段(T11~L2)为多发节段,占76.96%。2887例住院患者中,2611例患者(90.44%)采用微创手术治疗。患者住院过程中进行抗骨质疏松治疗的占患者总数的24.64%,且呈逐年增长趋势,差异有统计学意义(P<0.05)。患者发生二次骨折再次住院率为15.34%。微创手术的住院费用低于开放手术,且微创手术的住院日短于开放手术患者,差异有统计学意义(P<0.05)。结论:老年骨质疏松脊柱压缩性骨折在女性中的发病率高于男性,其中男性主要集中在70~79岁,而女性主要集中在60~69岁;骨折多发于胸腰段。老年骨质疏松脊柱压缩性骨折的治疗方式主要以微创手术为主,但患者存在二次骨折的风险。住院患者接受抗骨质疏松治疗的比例逐年增加。 Objective To analyze the epidemiological characteristics and treatment information of elderly patients with osteoporotic vertebral compression fractures(OVCFs)admitted to the hospital,and to provide data support for the prevention and treatment of the disease.Methods Data of 2887 hospitalized patients with OVCFs admitted to Xuzhou Central Hospital from January 1,2010,to August 31,2020,including age,gender,treatment modalities,hospitalization expenses,length of stay,occurrence of secondary fractures during hospitalization,comorbidities,etc,were collected.The gender and age characteristics of the disease,distribution of fractured vertebral bodies,and annual changes in the rate of anti-osteoporosis treatment were analyzed.Results Female patients outnumbered male patients in all age groups,with statistically significant differences(P<0.05).Among male patients,the age group with the highest number of cases was 70-79 years old,while among female patients,it was 60-69 years old.Among the 2887 hospitalized patients,a total of 3637 vertebral bodies were fractured,mostly distributed in the thoracolumbar spine(T11-L2),accounting for 76.96%.Among the 2887 hospitalized patients,2611 patients(90.44%)underwent minimally invasive surgery.The proportion of patients receiving anti-osteoporosis treatment during hospitalization was 24.64%,showing an increasing trend annually,with statistically significant differences(P<0.05).The readmission rate for patients with secondary fractures was 15.34%.The hospitalization expenses for minimally invasive surgery were lower than those for open surgery,and the length of hospital stay for minimally invasive surgery patients was shorter than that for open surgery patients,with statistically significant differences(P<0.05).Conclusions The incidence of OVCFs in elderly females is higher than that in males,with males mainly concentrated in the 70-79 age group and females mainly in the 60-69 age group.OVCFs are more common in the thoracolumbar spine.Minimally invasive surgery is the main treatment mo
作者 姜效韦 朱冬梅 王明宇 孙玉珠 张杨梅 JIANG Xiaowei;ZHU Dongmei;WANG Mingyu;SUN Yuzhu;ZHANG Yangmei(Department of Rehabilitation Medicine,Xuzhou Rehabilitation Hospital Affiliated to Xuzhou Medical University(Xuzhou City Rehabilitation Hospital),Xuzhou,Jiangsu 221018,China;Department of Rehabilitation Medicine,Xuzhou Central Hospital,Xuzhou,Jiangsu 220019,China)
出处 《医药前沿》 2024年第15期8-11,15,共5页 Journal of Frontiers of Medicine
基金 国家自然科学基金(81502435) 江苏省自然科学基金(BK20201153) 徐州市临床技术骨干研修计划项目(2019GG003) 徐州医科大学附属医院发展基金项目(XYFY2021035)。
关键词 骨质疏松症 脊柱压缩性骨折 流行病学特点 调查研究 Osteoporosis Spinal compression fracture Epidemiological characteristics Investigation and research
  • 相关文献

参考文献8

二级参考文献63

  • 1卫生部卫生统计信息中心北京协和医院世界卫生组织疾病分类合作中心编.国际疾病分类(ICD-10)应用指导手册[M].中国协和医科大学出版社,2001. 被引量:2
  • 2郭世,罗先正,邱贵兴主编.骨质疏松基础与临床[M].天津科学技术出版社,2001:6. 被引量:1
  • 3王嵘,邱勇.Neurotrophin 3对本体感觉神经作用的研究进展[J].医学研究生学报,2007,20(7):774-775. 被引量:3
  • 4Papaioannou A,Kennedy CC,Ioannidis G,et al.The impact of incident fractures on health-related quality of life:5 years of data from the Canadian Multicentre Osteoporosis Study.Osteoporos Int,2009,20:703-714. 被引量:1
  • 5Bouxsein ML,Kaufman J,Tosi L,et al.Recommendations for optimal care of the fragility fracture patient to reduce the risk of future fracture.J Am Acad Orthop Surg,2004,12:385-395. 被引量:1
  • 6Kanis JA,on behalf of the World Health Organization Scientific Group.Assessment of osteoporosis at the primary health-care level.Technical Report,UK:WHO Collaborating Centre,University of Sheffield,2008. 被引量:1
  • 7Hajcsar EE,Hawker G,Bogoch ER.Investigation and treatment of osteoporosis in patients with fragility fractures.CMAJ,2000,163:819-822. 被引量:1
  • 8Shea B,Wells G,Graney A,et al.Calcium supplementation on bone loss in postmenopausal women.J Cochrane Database Syst Rev,2007,1:D004526. 被引量:1
  • 9Marcus R,Wong M,Heath H,et al.Antiresorptive treatment of postmenopausal osteoporosis:comparison of study designs and outcomes in large clinical trials with fracture as an endpoint.Endocr Rev 2002;23:16-37. 被引量:1
  • 10Laurent C.Effects of osteoporosis medications on bone quality.Joint Bone Spine,2007,74:39-47. 被引量:1

共引文献1454

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部