摘要
目的分析谷胱甘肽和舒肝宁治疗慢性乙型肝炎的临床疗效。方法选取2022年1月—2023年1月本院收治的120例慢性乙型肝炎患者为研究对象,按照随机数字表法分为对照组和观察组,每组60例。对照组采用舒肝宁注射液进行治疗,观察组在此基础之上联合谷胱甘肽进行治疗。对比两组患者治疗前后肝功能相关数值的变化,以及两组患者的综合治疗有效率、不良反应发生情况。结果治疗前,两组患者肝功能TBIL、ALT、AST数值无显著差异(P>0.05);治疗后,观察组的肝功能数值优于对照组,两组差异有统计学意义(P<0.05)。观察组综合治疗有效率高于对照组,两组差异有统计学意义(P<0.05)。两组患者在治疗安全性方面,不良反应无显著差异(P>0.05)。结论谷胱甘肽联合舒肝宁注射液治疗慢性乙型肝炎,具有良好的临床效果,能够取得良好的治疗安全性并改善患者的症状,提高患者综合治疗的有效率,同时治疗手段较为安全,并不会带来新的不良反应,对于慢性乙型肝炎患者的综合治疗来说,具备显著效果可推广。
Objective To analyze clinical effect of glutathione and Shuganning in treatment of chronic hepatitis B.Methods The paper chose 120 patients with chronic hepatitis B in our hospital from January 2022 to January 2023.Control group was treated with Shuganning injection for treatment,while observation group with combined treatment with glutathione on the basis.Changes in liver function related values before and after treatment,incidence of adverse reactions in comprehensive treatment effect were compared between two groups.Results There was no significant difference in TBIL,ALT,and AST values of liver function between observation group and treatment group before treatment,which wsa comparable between groups,P>0.05.After treatment,liver function values of observation group were better than control group,there was significant difference between two groups P<0.05.Comprehensive treatment effect rate of observation group was 90%,higher than 72%in control group.There was significant difference between two groups,P<0.05.There was no significant difference in treatment safety between observation group and control group,there was no significant difference in adverse reactions between two groups,P>0.05.Conclusion Combination of glutathione and Shuganning injection can achieve good clinical effect in treatment of chronic hepatitis B,can achieve good treatment safety,improve patient symptoms,and comprehensive treatment effect,with significant effect and no new adverse reactions in comprehensive treatment of chronic hepatitis B patients,which can be promoted.
作者
陈永一
CHEN Yongyi(Taonan City People's Hospital,Taonan,Jilin,137100)
出处
《智慧健康》
2024年第9期60-63,71,共5页
Smart Healthcare
