摘要
嗜铬细胞瘤/副神经节瘤(pheochromocytoma/paraganglioma,PPGL)相关儿茶酚胺心肌病是由于PPGL分泌的过量儿茶酚胺引起的心脏结构改变和功能异常,是一种潜在的致命性心血管并发症。根据心脏的形态及功能,临床上将其分为扩张型心肌病、Takotsubo心肌病和肥厚型心肌病3种类型。PPGL相关儿茶酚胺心肌病的治疗需重视药物的选择、生命支持设备的应用和围手术期处理,多数患者的心功能异常在肿瘤切除后可以有效改善。该文主要对PPGL相关儿茶酚胺心肌病的诊治进行综述。
Catecholamine-induced cardiomyopathy in pheochromocytoma/paraganglioma(PPGL)is a potential fatal cardiovascular complication caused by excessive secretion of catecholamines by PPGL,leading to structural changes and functional abnormalities in the heart.According to the morphology and function of the heart,it is clinically divided into three types:dilated cardiomyopathy,Takotsubo cardiomyopathy,and hypertrophic cardiomyopathy.The treatment of catecholamine-induced cardiomyopathy in PPGL requires attention to drug selection,application of life support equipment,and perioperative management.Most patients with cardiac dysfunction can effectively improve after tumor resection.This article mainly reviews the diagnosis and treatment of catecholamine-induced cardiomyopathy in PPGL.
作者
肖云峰
杨宗珂
XIAO Yunfeng;YANG Zongke(School of Clinical Medicine,North Sichuan Medical College,Nanchong,Sichuan 637000,P.R.China;Department of Urology,Dianjiang County People’s Hospital,Chongqing 408300,P.R.China)
出处
《华西医学》
CAS
2024年第4期635-639,共5页
West China Medical Journal
