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臭氧注射在神经根型颈椎病患者颈神经阻滞后的应用及对患者炎性疼痛的影响

Application of Ozone Injection in Cervical Nerve Block in Patients with Radiculotic Cervical Spondylosis and Its Effect on Inflammatory Pain
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摘要 目的研究分析臭氧注射在神经根型颈椎病患者颈神经阻滞后的应用及对炎性疼痛的影响。方法便利选取2021年5月—2023年5月解放军联勤保障部队第九〇七医院收治的84例神经根型颈椎病患者为研究对象,依据随机数表法分为两组,各42例。对照组行颈神经阻滞治疗,观察组在对照组的基础上接受臭氧注射治疗,比较两组临床疗效、颈肩疼痛程度、颈椎功能以及血清炎性指标。结果观察组总有效率(97.62%)高于对照组(80.95%),差异有统计学意义(χ^(2)=4.480,P=0.034)。观察组治疗后1、12周视觉模拟评估法(Visual Analog Scale,VAS)得分、颈椎功能障碍指数(Neck Dysfunction Index,NDI)得分低于对照组,差异有统计学意义(t=3.017、5.645、2.275、3.360,P均<0.05)。治疗后观察组超敏C反应蛋白(High Sensitivity C-reactive Protein,hs-CRP)、白细胞介素-6(Interleukin-6,IL-6)、白细胞介素-8(Interleukin-8,IL-8)水平低于对照组,差异有统计学意义(t=4.936、2.545、2.879,P均<0.05)。结论臭氧注射在神经根型颈椎病患者颈神经阻滞后的应用效果显著,利于减轻炎性疼痛症状,加快颈椎功能恢复。 Objective To study and analyze the effect of ozone injection on inflammatory pain after cervical nerve block in patients with radiculotic cervical spondylosis.Methods A total of 84 patients with radiculotic cervical spondylosis admitted to the 907 Hospital of PLA Joint Logistic Support Force from May 2021 to May 2023 were conveniently selected as the study objects and were divided into two groups with 42 patients in each group according to random number table method.The control group received cervical nerve block treatment alone,and the observation group received ozone injection treatment based on the treatment of control group.The clinical efficacy,degree of neck and shoulder pain,cervical function and serum inflammatory indexes were compared between the two groups.Results The total effective rate of the observation group(97.62%)was higher than that of the control group(80.95%),the difference was statistically significant(χ^(2)=4.480,P=0.034).Visual Analogue Scale(VAS)scores and Neck Dysfunction Index(NDI)scores in the observation group were lower than those in the control group 1,12 weeks after treatment,the differences were statistically significant(t=3.017,5.645,2.275,3.360,all P<0.05).After treatment,the levels of High Sensitivity C-reactive Protein(hs-CRP),Interleukin-6(IL-6)and Interleukin-8(IL-8)in the observation group were lower than those in the control group,the differences were statistically significant(t=4.936,2.545,2.879,all P<0.05).Conclusion Ozone injection has a remarkable effect on cervical nerve block in patients with radiculotic cervical spondylosis,which is beneficial to alleviate inflammatory pain symptoms and accelerate cervical function recovery.
作者 张伟 ZHANG Wei(Department of Orthopedics,the 907 Hospital of PLA Joint Service Support Force,Nanping,Fujian Province,353000 China)
出处 《中外医疗》 2024年第8期51-54,共4页 China & Foreign Medical Treatment
关键词 神经根型颈椎病 臭氧注射 颈神经阻滞 炎性疼痛 Radiculotic cervical spondylosis Ozone injection Cervical nerve block Inflammatory pain
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