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麻醉药物对肿瘤患者免疫功能的影响

Effects of Anesthetics on Immune Function in Patients with Tumor
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摘要 人体免疫系统包括先天性免疫和获得性免疫两大部分,为宿主抵抗病原体和肿瘤侵袭发挥重要作用。大量研究试图了解麻醉药物对免疫功能的影响。本文综述最常见的麻醉药物对肿瘤患者先天性免疫和获得性免疫的影响,包括吸入性麻醉药、静脉麻醉药、阿片类药物以及局部麻醉药。每一种麻醉药物对免疫系统有独特的影响,对于肿瘤患者需制定适合患者的特异性治疗策略,以优化短期和长期的手术疗效。 The immune system is classically divided into innate and adaptive components,which play an important role in the host’s resistance to pathogens and tumor invasion.A large number of studies have attempted to understand the effects of anesthetics on immune function.The most commonly used anesthetic agents were chosen in this review including volatile agents,intravenous agents,opioids,and local anesthetics.Each has unique effect on the immune system.Specific treatment strategies need to be developed to improve short and long term surgical outcomes for patients with malignant tumors.
作者 黄丽丽 张铁军 Lili Huang;Tiejun Zhang(The State Key Laboratory of Oral&Maxillofacial Reconstruction and Regeneration,Key Laboratory of Oral Biomedicine Ministry of Education,Hubei Key Laboratory of Stomatology,School&Hospital of Stomatology,Wuhan University;Department of Anesthesiology,School and Hospital of Stomatology,Wuhan University)
出处 《中国口腔医学继续教育杂志》 2023年第6期474-478,488,共6页 Chinese Journal of Stomatologial Continuing Education
基金 湖北省自然科学基金面上项目(项目编号:2022CFB065)。
关键词 麻醉药物 免疫功能 肿瘤患者 肿瘤转移 手术 anesthetics immune tumor patients tumor metastasis surgery
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