摘要
An efficient N–H and C(sp~3)-H functionalization of aryl ketones with benzylamines/amino acids was developed under mild conditions by virtue of anodic oxidation. A variety of functionalized 2,5-diaryloxazoles were obtained with good to excellent yields. Moreover, some important natural products can be prepared by this method. The reaction features a broad substrate scope, scalability, metal-free and chemical oxidant-free.
基金
the financial support from the National Natural Science Foundation of China (Nos.21772185
22001241)
the support from the Science and Technology Major Project of Anhui Province of China (No.201903a07020003)
the Science and Technology Major Project of Fuyang of Anhui Province of China(No.FK20208018)。
