摘要
以《中国药典》(2020年版及第一增补本)、《国家基本医疗保险、工伤保险和生育保险目录》(2022年版)、《国家基本药物目录》(2018年版)收载的儿童中成药为研究对象,梳理分析儿童中成药(包括儿童专用药、儿童成人共用药、儿童酌减类药)分布现状、特点及可能存在的问题。经归纳统计,儿童中成药给药途径以口服为主,多为片剂、颗粒剂、胶囊剂、口服液等传统剂型,口感多为苦、甜,治疗病种主要分布在肺系疾病及脾胃疾病,安全用药信息缺失或“尚不明确”品种占比较大。我国儿童中成药存在专用品种较少、用药顺应性欠佳、用法用量欠细化、安全用药信息欠完善等问题,建议及时更新完善药品说明书,开发儿童中成药新品种,积极开展儿童中成药上市后评价及临床综合评价工作,为儿童中成药药品说明书补充完善、儿童中成药全面提升、儿童中成药目录制定及新药研发提供参考,保障用药。
This study took Chinese patent medicine for children included in Chinese Pharmacopoeia(2020 edition and the first supplement),Medicine Catalogue for National Basic Medical Insurance,Work Injury Insurance,and Maternity Insurance(2022 edition),and National Essential Medicines List(2018 edition)as the research objects,so as to sort out the distribution situation,characteristics,and the problems of Chinese patent medicine for children(including child-specific medicines,common medicines for children and adults,and discretionary medicines for children).According to statistics and summary,Chinese patent medicine for children is mainly administered orally,and the dosage forms are mostly traditional dosage forms,such as tablets,granules,capsules,and oral liquids,with mostly bitter or sweet taste.Diseases are mainly classified into pulmonary diseases and spleen and stomach diseases,and varieties of medication without Children′s medication safety information or"still unclear"account for a relatively large proportion of the medicines.There are relatively few varieties of Chinese patent medicines for children,poor compliance of childspecific medication,lack of refinement of Chinese patent medicines for children dosage,and lack of information about safe use of medication.It is recommended to update and improve the instruction manuals in a timely manner,develop new varieties of Chinese patent medicine for children,and actively carry out post-marketing evaluation and clinical comprehensive evaluation of Chinese patent medicine for children,so as to provide a reference for the supplement and improvement of the instructions,the comprehensive improvement,the formulation of the catalogue,and the research and development of new Chinese patent medicine for children and ensure the use of medicines for children.
作者
刘晖
陈宇静
付乾芳
赵书艺
聂良卉
马榕
戎萍
LIU Hui;CHEN Yu-jing;FU Qian-fang;ZHAO Shu-yi;NIE Liang-hui;MA Rong;RONG Ping(First Teaching Hospital of Tianjin University of Traditional Chinese Medicine,Tianjin 300381,China;National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion,Tianjin 300381,China)
出处
《中国中药杂志》
CAS
CSCD
北大核心
2024年第7期1966-1973,共8页
China Journal of Chinese Materia Medica
基金
中华中医药学会求实项目(儿科专项)(2022-QSEKZX-04)
国家中医药管理局青年岐黄学者支持项目(国中医药人教函[2021]204号)。
关键词
儿童
中成药
合理用药
children
Chinese patent medicine
rational use of medication
