摘要
目的探讨基于孕期MRI检查的原始数据集采用阈值分割方式构建子宫颈数字化三维模型的方法及意义。方法本研究为前瞻性研究,共招募了2023年6至8月在中国医科大学附属盛京医院进行盆腔MRI检查的12例健康孕妇,包括6例孕中期、6例孕晚期,利用快速平衡稳态采集序列获得层厚为4 mm、层间距为0 mm的MRI原始数据集,将原始数据集导入Mimics软件中进行子宫颈数字化三维重建,同时测量并比较孕中期与孕晚期孕妇子宫颈长度、直径、前角和后角、内口面积、表面积及体积等各项参数。采用独立样本t检验和Mann-WhitneyU检验进行统计学分析。结果12例孕妇均成功重建孕期子宫颈的数字化三维模型,该模型可以多视角、多平面地观察子宫颈的整体形态和结构,并可对子宫颈进行三维测量。孕中期孕妇的子宫颈长度[(4.15±0.80)与(2.71±0.72)cm]、子宫颈体积[(42.58±9.24)与(28.44±10.18)cm3]和子宫颈长度与直径比值(1.06±0.21与0.72±0.19)明显大于孕晚期(t值分别为3.30、-2.52及-2.98,P值均<0.05),但子宫颈内口面积明显小于孕晚期[(18.56±5.97)与(27.68±4.72)mm2,t=2.93,P=0.016];孕中期与孕晚期的子宫颈前角、后角及表面积比较差异均无统计学意义(P值均>0.05)。结论基于MRI数据利用阈值分割的三维重建方法可以构建在体孕期子宫颈数字化三维模型,模型能够立体呈现孕期子宫颈的形态学特征,显示不同孕周子宫颈的结构差异,为孕期子宫颈的孕期监测、形态学观察及定量研究提供了新的方法。
Objective To investigate the method of constructing a digitalized three-dimensional(3D)model of the cervix based on threshold segmentation of raw data sets from prenatal MRI examinations.Methods In this prospective study,12 healthy pregnant women who underwent pelvic MRI scans at Shengjing Hospital of China Medical University between June and August 2023 were recruited,including six in the second trimester and six in the third trimester.The original MRI datasets with a slice thickness of 4 mm and an interslice gap of 0 mm were obtained using fast imaging employing steady-state acquisition sequences,and then imported into Mimics software for digital 3D reconstruction of the cervix uteri.Several parameters of the cervix uteri including the length,diameter,anterior angle,posterior angle,internal os area,surface area,and volume were measured and compared between the women in different trimesters.Statistical analysis was conducted using independent sample t-test and Mann-Whitney U test.Results The digital 3D model of the cervix uteri during pregnancy was successfully constructed for all 12 pregnant women.The model enabled the multi-angle and multiplanar observation of the overall morphology and structure of the cervix uteri,as well as 3D measurements.The cervical length[(4.15±0.80)vs.(2.71±0.72)cm],cervical volume[(42.58±9.24)vs.(28.44±10.18)cm³],and the ratio of cervical length to diameter(1.06±0.21 vs.0.72±0.19)of the mid-trimester women were significantly greater than those of the late-trimester women(t=3.30,-2.52 and-2.98,respectively;all P<0.05).However,the internal os area in the second trimester was smaller than that in the third trimester[(18.56±5.97)vs.(27.68±4.72)mm2,t=2.93,P=0.016].There was no significant difference in the anterior angle,posterior angle,or surface area of the cervix uteri between women in the second and third trimesters(all P>0.05).Conclusion The method of digital 3D reconstruction based on threshold segmentation of MRI data can construct digital 3D models of the cervix during pre
作者
刘强
张国安
乞文旭
Liu Qiang;Zhang Guoan;Qi Wenxu(Department of Radiology,Shengjing Hospital of China Medical University,Shenyang 110004,China;Department of Radiology,the Seventh Clinical College,China Medical University,Fushun 113012,China)
出处
《中华围产医学杂志》
CAS
CSCD
北大核心
2024年第4期317-321,共5页
Chinese Journal of Perinatal Medicine
基金
辽宁省教育厅基本科研面上项目(LJKMZ20221156)。
关键词
子宫颈
磁共振成像
数字化三维模型
Cervix uteri
Magnetic resonance imaging
Digital three-dimensional model
