摘要
多数心血管疾病对于患者的危害性是致命的。心血管疾病一般不可逆转,其治疗的重点聚焦于延缓病情发展的对症治疗,因此开发新疗法至关重要。脂质纳米颗粒(LNPs)有纳米尺寸以及脂化合物的普遍优势,能够克服其他靶向载体固有缺陷,因此有应用于心血管疾病的潜力。本文围绕LNPs在各种心血管疾病中应用的最新进展进行综述。
Most cardiovascular diseases are fatal to patients.These diseases are generally irreversible,the focus of treatment is on symptomatic treatment to delay the progression of the disease.Therefore,developing new therapies is crucial.Lipid nanoparticles(LNPs)have the general advantages of nano size and lipid compounds,and they can overcome the inherent defects of other targeted carriers,so they have the potential for clinical application in cardiovascular diseases.This article reviews the latest progress in the application of LNPs in various cardiovascular diseases.
作者
张彤
唐其柱
ZHANG Tong;TANG Qizhu(Dept.of Cardiology,Renmin Hospital of Wuhan University,Wuhan 430060,Hubei,China;Hubei Key Laboratory of Metabolic and Chronic Disease,Wuhan 430060,Hubei,China)
出处
《武汉大学学报（医学版）》
CAS
2024年第4期501-504,共4页
Medical Journal of Wuhan University
基金
国家自然科学基金资助项目(编号:U22A20269)。
关键词
心血管疾病
纳米技术
基因治疗
分子影像
Cardiovascular Disease
Nanotechnology
Gene Therapy
Molecular Image
