摘要
目的:通过观察Wood灯下白癜风患者治疗过程中皮损的复色模式,探究不同复色模式的相关影响因素,分析评估不同复色模式间的疗效差异。方法:收集选取2021年8月-2022年8月笔者医院就诊的90例(170块),采集患者基本信息及病情相关指标。治疗后,观察Wood灯下皮损复色模式,将复色模式与收集指标进行统计分析,筛选出差异有统计学意义的指标后,采用Logistic回归分析阳性指标与复色模式的相关性。并将Wood灯下观察的皮损面积作为疗效判定标准,分析对比不同复色模式间的疗效差异。结果:One-way ANOVA分析、χ^(2)检验显示白癜风疾病分期、皮损部位、治疗方式与皮损复色模式有关(P<0.05)。Logistic回归分析显示:治疗方式与复色模式存在相关性(P<0.05)。不同复色模式达到有效复色面积的时间比较,差异有统计学意义(H=8.04,P<0.05)。结论:通过观察Wood灯下白癜风患者治疗过程中皮损的复色模式发现,治疗方式可能是白癜风皮损复色模式的决定因素;不同复色模式之间的复色速度存在差异,可作为临床医师调整治疗方案的参考依据。
Objective The purpose of this study was to observe the repigmentation patterns of vitiligo during the treatment process using the Wood's lamp,explore the relevant influencing factors of different repigmentation patterns,and analyze and evaluate the efficacy differences between different repigmentation patterns.Methods A total of 90 vitiligo cases(170 lesions)attending the author's hospital from August 2021-August 2022 were collected,and basic information and disease-related indicators of the patients were collected.After treatment,the repigmentation patterns of the lesions were observed under the Wood's lamp,and statistical analysis was performed on the collected indicators.After screening out the indicators with statistically significant differences,the logistic regression analysis was used to analyze the correlation between the positive indicators and the repigmentation patterns.The area of the lesion observed under the Wood's lamp was used as the standard for efficacy assessment,and the efficacy differences between different repigmentation patterns were analyzed and compared.Results The results showed that vitiligo disease stage,lesion site,treatment method,and repigmentation pattern were related(P<0.05)according to One-way ANOVA analysis and χ^(2) test.The logistic regression analysis showed that there was a correlation between treatment method and repigmentation pattern(P<0.05).The time it took for different repigmentation patterns to reach effective repigmentation areas was compared(H=8.04,P<0.05),and the difference was statistically significant.Conclusion The treatment method may be a determining factor for the repigmentation pattern of vitiligo lesions,and the different repigmentation speeds between different repigmentation patterns can be used as a reference for clinicians to adjust treatment plans.
作者
金伟梅
马杰
索翠平
车旭
赵建斌
JIN Weimei;MA Jie;SUO Cuiping;CHE Xu;ZHAO Jianbin(Department of Dermatology,the Affiliated Hospital of Xuzhou Medical University,Xuzhou 221112,Jiangsu,China;Medical Records and Data Statistics Center,the Affiliated Hospital of Xuzhou Medical University,Xuzhou 221112,Jiangsu,China)
出处
《中国美容医学》
CAS
2024年第5期103-107,共5页
Chinese Journal of Aesthetic Medicine
关键词
白癜风
复色模式
治疗方式
复色速度
Wood灯
vitiligo
repigmentation patterns
treatment method
repigmentation speed
Wood's lamp
