摘要
目的:探讨不同脑区血管周围间隙(PVS)数目进展和急性缺血性脑卒中(AIS)发生的相关性。方法:回顾性纳入205例伴有PVS患者前后两次头颅MRI检查的影像资料,收集相关临床资料,根据末次检查时是否合并AIS分为急性缺血性脑卒中组(以下简称卒中组)及对照组,比较两组间相关指标的差异。采用多因素logistic回归法分析AIS发生的危险因素。结果:卒中组既往发生脑梗比例、舒张压水平、PVS数目进展均高于对照组(P<0.05)。在卒中组中,基底节区PVS数目进展程度明显高于半卵圆中心(P<0.001)。多因素logistic回归分析显示,舒张压水平、脑梗史、基底节PVS变化(ΔPVS)数目是AIS发生的危险因素(P<0.05)。结论:PVS数目的进展与AIS的发生具有一定的相关性,是AIS发生发展的重要危险因素。
Purpose:To explore the correlation between the progression of perivascular spaces(PVS)number in different brain regions and the occurrence of acute ischemic stroke(AIS).Methods:The imaging data of two cranial MRI examinations in 205 patients with PVS were retrospectively included,and the relevant clinical data were collected.According to whether AIS was combined at the last examination,the patients were divided into an acute ischemic stroke group(hereinafter referred to as stroke group)and a control group,and the differences of relevant indicators between the two groups were compared.Multivariate logistic regression was used to analyze the risk factors of AIS.Results:In the stroke group,the proportion of former cerebral infarction,the diastolic blood pressure,and the progression of PVS number were higher than those in the control group(P<0.05).The progression in the number of PVS in the basal ganglia of the stroke group was significantly higher than that in the centrum semiovale(P<0.001).Multivariate logistic regression analysis showed that diastolic blood pressure,cerebral infarction history and the number of ΔPVS in basal ganglia were risk factors for AIS(P<0.05).Conclusion:The progression of the number of PVS has a certain correlation with the occurrence of AIS,and is an important risk factor for the occurrence and development of AIS.
作者
王绍才
王伟
崇立娟
徐含波
胡梦雪
徐凯
WANG Shaocai;WANG Wei;CHONG Lijuan;XU Hanbo;HU Mengxue;XU Kai(Department of Radiology,Affiliated Hospital of Xuzhou Medical University,Xuzhou 221000,China)
出处
《中国医学计算机成像杂志》
CSCD
北大核心
2024年第2期141-145,共5页
Chinese Computed Medical Imaging
基金
徐州医科大学附属医院院级课题基金(2021ZA31)。
