摘要
目的探讨屈螺酮炔雌醇片联合坤灵丸对未育女性重复人工流产术后生殖健康的影响。方法选取2016年10月至2017年10月于惠州卫生职业技术学院附属医院行人工流产术的360例未育重复人工流产患者作为研究对象,按照随机数字表法分为优思明组、联合组与对照组,每组120例。优思明组采用屈螺酮炔雌醇片治疗,联合组采用屈螺酮炔雌醇片联合坤灵丸治疗,对照组不服用上述药物,比较3组术后阴道出血时间、阴道分泌物、月经复潮时间、月经恢复情况、子宫内膜厚度、宫颈宫腔粘连、宫内残留、盆腔炎性疾病、点滴出血等情况。结果3组月经复潮时间、月经规律情况比较差异有统计学意义(P<0.05);优思明组、联合组月经复潮时间均短于对照组,联合组月经复潮时间长于优思明组,且联合组月经规律情况优于优思明组、对照组,差异有统计学意义(P<0.05)。优思明组与对照组月经规律情况比较差异无统计学意义。优思明组、联合组阴道出血时间短于对照组,阴道分泌物增多、阴道炎比例均低于对照组,联合组阴道出血时间短于优思明组,差异有统计学意义(P<0.05)。优思明组、联合组术后15d子宫内膜厚度均厚于对照组,宫颈宫腔粘连、宫内残留、盆腔炎性疾病比例均低于对照组,联合组点滴状出血比例低于优思明组、对照组,差异有统计学意义(P<0.05)。结论屈螺酮炔雌醇片联合坤灵丸治疗未育女性重复人工流产术后效果显著,可有效缩短阴道流血事件,恢复患者月经周期,减少阴道分泌物,预防宫腔粘连、盆腔炎和痛经的发,减少未育女性非意愿妊娠发生和再次流产的危害,保留生育功能,值得临床推广应用。
Objective To investigate the effect of drospirenone and ethinylestradiol tablets combined with Kunling pills on reproductive health of nulliparous women after repeated artificial abortion.Methods A total of 360 patients with repeated abortion who underwent artificial abortion in Affiliated Hospital of Huizhou Health Vocational and Technical College from October 2016 to October 2017 were selected as the research subjects,they were divided into Yasmin group,combined group and control group,with 120 cases in each group.The Yasmin group was treated with drospire-none and ethinylestradiol tablets,the combined group was treated with drospirenone and ethinylestradiol tablets combined with Kunling pills,and the control group was not treated with the above drugs.The postoperative vaginal bleeding time,vaginal secretion,menstrual recovery time,menstrual recovery,endometrial thickness,cervical intrauterine adhesion,intrauterine residue,pelvic inflammatory disease and spotting bleeding were com-pared among the three groups.Results There were significant differences in menstrual recovery time and menstrual regularity among the three groups(P<0.05).The time of menstrual recovery in the Yasmin group and the combined group was shorter than that in the control group,and the time of menstrual recovery in the combined group was longer than that in the Yasmin group,and the menstrual regularity in the combined group was better than that in the Yasmin group and the control group,the differences were statistically significant(P<0.05).There was no significant difference in menstrual regularity between the Yasmin group and the control group.The vaginal bleeding time in the Yasmin group and the combined group was shorter than that in the control group,the proportion of vaginal secretions and vaginitis was lower than that in the control group,and the vaginal bleeding time in the combined group was shorter than that in the Yasmin group,the differences were statistically significant(P<0.05).The endometrial thickness of the Yasmin group and t
作者
姚伟妍
唐娟
YAO Weiyan;TANG Juan(Affiliated Hospital of Huizhou Health Vocational and Technical College,Huizhou,Guangdong,516000,China)
出处
《当代医学》
2023年第30期106-109,共4页
Contemporary Medicine
基金
惠州市科学技术局资助项目(2021WC0106473)。
