摘要
目的探讨心脏骤停(CA)患者呼气末二氧化碳分压(P_(ET)CO_(2))与自主循环恢复(ROSC)的关系研究。方法回顾性选取2018年5月~2023年5月就诊于北京大学第三医院秦皇岛医院急诊科及重症医学科成人CA患者107例的数据。分析CA患者P_(ET)CO_(2)水平与ROSC的关系。结果107例CA患者经心肺复苏术(CPR)抢救治疗后,73例患者自主循环恢复设为ROSC组,34例患者复苏失败设为无ROSC组。ROSC组在10、20和30 min时P_(ET)CO_(2)均高于无ROSC组,差异有统计学意义(t=29.457、56.934、51.801,P<0.05)。107例CA患者中共有67例患者存活(存活组),40例患者死亡(死亡组)。两组0 min时P_(ET)CO_(2)差异无统计学意义(t=0.504,P=0.615);存活组在10、20和30 min时P_(ET)CO_(2)均高于死亡组,差异有统计学意义(t=16.955、14.757、17.071,P<0.05);P_(ET)CO_(2)、CA对ROSC造成影响时,标准化路径系数分别为0.182、0.187、0.353,路径呈现出的0.05水平的显著性(Z=2.283、2.340、5.798,P<0.05)。结论CA患者P_(ET)CO_(2)水平与ROSC的关系为正向影响关系,可以监测并预估患者CPR质量。
Objective To investigate the study of the relationship between partial pressure of end-expiratory carbon dioxide(P_(ET)CO_(2))and recovery of autonomic circulation(ROSC)in patients with cardiac arrest(CA).Methods Data from 107 adult CA patients who attended the emergency department and department of critical care medicine of Qinhuangdao Hospital,Peking University Third Hospital from May 2018 to May 2023 were selected for retrospective study.The relationship between P_(ET)CO_(2)levels and ROSC in CA patients was analyzed.Results In 107 CA patients,after CPR resuscitation treatment,73 patients with recovery of autonomic circulation were set as ROSC group.34 patients with resuscitation failure were set as no ROSC group.There was no difference in the comparison of age,gender,CPR start time,CPR end time,ventilation mode,ECC mode,epinephrine dose,defibrillation times and other data between the two groups(P>0.05).P_(ET)CO_(2)was higher in the ROSC group than the no-ROSC group at 10 min,20 min and 30 min(P<0.05).Among 107 patients,67 patients survived and 40 patients died.There was no difference in P_(ET)CO_(2)at 0 min between the survival group and the death group(P>0.05),and P_(ET)CO_(2)in the survival group was higher than that in the death group at 10 min,20 min,and 30 min(P<0.05).The standardised path coefficients of P_(ET)CO_(2)and CA when they had an effect on ROSC were 0.182,0.187,and 0.353,respectively,which were>0.The paths showed a significance at the 0.05 level(Z=2.283,2.340,5.798,P<0.05),indicating a positive relationship of P_(ET)CO_(2),CA on ROSC.Conclusion The relationship between P_(ET)CO_(2)level and ROSC in CA patients is a positive influence relationship,which can monitor and predict the quality of CPR in patients.
作者
王晓蕾
王秋艳
于美军
陈静
曾君
李力平
吴双
Wang Xiaolei;Wang Qiuyan;Yu Meijun(Department of Critical Care Medicine,Peking University Third Hospital Qinhuangdao Hospital,Qinhuangdao 066000,China)
出处
《中华保健医学杂志》
2024年第2期159-161,共3页
Chinese Journal of Health Care and Medicine
基金
秦皇岛科技计划项目(202301A083)。
关键词
心脏骤停
呼气末二氧化碳分压
自主循环恢复
Cardiac arrest
Partial pressure of carbon dioxide at end-expiration
Recovery of autonomic circulation
