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复发性耳部瘢痕疙瘩的多模式治疗效果

Effect of multimodal treatment on recurrent ear keloids
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摘要 目的 探讨复发性耳部瘢痕疙瘩的形态特征及一期多模式治疗的效果。方法 回顾性分析自2019年8月至2022年8月,新疆医科大学第一附属医院整形科采用手术、电子线照射、硅酮药物及同位素一期多模式治疗36例(49只耳)复发性耳部瘢痕疙瘩患者,根据瘢痕疙瘩的位置、大小以及表面皮肤是否正常等特征选择不同的手术方式,术后外用硅酮药物及硅胶耳夹压迫治疗,其中16例患者通过手术+电子线照射+外用硅酮+压迫+同位素治疗(A方案);18例患者通过手术+电子线照射+外用硅酮+压迫治疗(B方案);手术+外用硅酮+压迫+同位素治疗(C方案)及手术+外用硅酮+压迫治疗(D方案)各有1例。术后1、3、6、12个月分别复诊1次,对有复发倾向者及时补做同位素治疗,观察治疗后效果。结果 A方案治愈7例,有效9例,有效率为100%;B方案治愈8例,有效9例,无效1例,有效率为94.4%;C方案及D方案各有1例,均无效,有效率均为0。不同治疗方案治疗效果比较,差异均有统计学意义(P<0.05)。结论 根据复发性耳部瘢痕疙瘩的形态特征采用手术、电子线照射、硅酮药物及同位素一期多模式治疗能有效地提高治疗效果和降低复发率。 Objective To explore the morphological characteristics of recurrent ear keloids and the effect of one-stage multimodal treatment. Methods A retrospective analysis was performed on 36 patients(49 ears) with recurrent ear keloids admitted to the Department of Plastic Surgery, the First Affiliated Hospital of Xinjiang Medical University from August 2019 to August 2022. Different surgical methods were selected according to the location, size and whether the surface skin was normal. After surgery, external silicone ointment and silicone ear clips were used for compression treatment, and 16 patients were treated with surgery + electron beam irradiation + external silicone + compression + isotope(Scheme A);18 patients were treated with surgery + electron beam irradiation + external silicone + compression(Scheme B);1 patient was treated with surgery + external silicone + compression + isotope(Scheme C), and 1 patient was treated with surgery + external silicone + compression(Scheme D). The patients were followed up once 1, 3, 6, and 12 months after surgery, and isotopic treatment was performed in time for those with recurrence tendency, and the therapeutic effect was observed. Results In Scheme A, 7 cases were cured, 9 cases were effective, and the effective rate was 100%;in Scheme B, 8 cases were cured, 9 cases were effective,and 1 case was ineffective, and the effective rate was 94.4%;in Scheme C and Scheme D, there was 1 case in each, both ineffective, and the effective rate was 0. There were significant differences in the therapeutic effects of different treatment schemes(P<0.05). Conclusion According to the morphological characteristics of recurrent ear keloids, the use of surgery, electron beam irradiation, silicone ointment and isotope in a one-stage multimodal treatment can effectively improve the therapeutic effect and reduce the recurrence rate.
作者 李卫平 秦涛 于扬 马娟 董祥林 LI Weiping;QIN Tao;YU Yang;MA Juan;DONG Xianglin(Department of Plastic Surgery,the First Affiliated Hospital of Xinjiang Medical University,Urumqi 830054,China)
出处 《中国美容整形外科杂志》 CAS 2024年第3期171-174,共4页 Chinese Journal of Aesthetic and Plastic Surgery
基金 新疆维吾尔自治区自然科学基金资助项目(2019D01C308)。
关键词 瘢痕疙瘩 耳部 形态特征 多模式治疗 Keloid Ear Morphological characteristics Multimodal treatment
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