摘要
目的探讨生物电阻抗分析法(BIA)指导超滤量同常规临床方法相比对血液透析患者残余肾功能(RRF)的影响。方法计算机检索2022年12月31日前发表在PubMed、Cochrane Library、Embase、Web of Science等英文数据库以及中国知网、维普数据库、万方医学和中国生物医学文献数据库等中文数据库,探讨应用BIA指导超滤量同常规临床方法相比对血液透析患者RRF影响的随机对照试验(RCT),采用RevMan 5.4软件进行meta分析。结果最终纳入6篇文献,共计406名受试者。meta分析结果显示随访结束后BIA指导组的患者RRF(P<0.05,MD=1.15,95%CI:1.00~1.31)、24 h尿量(P<0.05,MD=253.56,95%CI:229.17~277.96)均高于对照组,超滤量(P<0.05,MD=-0.45,95%CI:-0.65~-0.26)及舒张压(P<0.05,MD=-5.52,95%CI:-7.58~-3.47)均低于对照组;两组患者的收缩压(P>0.05,MD=-0.25,95%CI:-7.70~7.21)、体质量(P>0.05,MD=-0.01,95%CI:-3.38~3.37)、白蛋白(P>0.05,MD=0.41,95%CI:-1.61~2.43)比较,差异均无统计学意义。结论基于现有研究,在营养管理及容量管理过程中采用BIA指导超滤量同常规临床方法相比有助于保护血液透析患者的RRF。
Objective To investigate the effect of bioimpedance analysis(BIA)-guided ultrafiltration on remaining renal function(RRF)in hemodialysis patients compared with conventional clinical methods.Methods PubMed,Cochrane Library,Embase,Web of Science,CNKI,Wanfang,VIP,and CBM were searched for randomized controlled trials(RCTs)about the effects of BIA-guided ultrafiltration on RRF in hemodialysis patients compared with conventional clinical methods from the inception to December 31,2022.Meta-analysis was performed by RevMan 5.4.Results A total of 6 RCTs with 406 participants were included.The results of meta-analysis showed that the RRF[P<0.05,MD=1.15,95%CI(1.00,1.31)]and 24 h urine output[P<0.05,MD=253.56,95%CI(229.17,277.96)]of the BIA guidance group were higher than those of the control group,and the ultrafiltration volume[P<0.05,MD=-0.45,95%CI(-0.65,-0.26)]and diastolic blood pressure[P<0.05,MD=-5.52,95%CI(-7.58,-3.47)]were lower than those of the control group,but there were no statistically significant differences in the systolic blood pressure[P>0.05,MD=-0.25,95%CI (-7.70, 7.21)], body weight [P>0.05, MD=-0.01, 95%CI (-3.38, 3.37)], or albumin [P>0.05, MD=0.41, 95%CI (-1.61, 2.43)] between the two groups. Conclusion Based on the existed data,compared with conventional clinical methods, BIA-guided ultrafiltration can protect the RRF inhemodialysis patients.
作者
蒋海丽
潘虹
矫春晓
丛丽娜
李海强
Jiang Haili;Pan Hong;Jiao Chunxiao;Cong Lina;Li Haiqiang(Nutriology Department,Yantai Yeda Hospital,Yantai 264006,China;Invasive Technology Department,Yantai Yeda Hospital,Yantai 264006,China;Blood Purification Center,Yantai Yeda Hospital,Yantai 264006,China)
出处
《国际医药卫生导报》
2024年第8期1301-1306,共6页
International Medicine and Health Guidance News
