摘要
溃疡性结肠炎(UC)是炎症性肠病的一种亚型,为慢性终身疾病,临床特征主要包括复发缓解过程、特发性肠道炎症、血性腹泻和体重减轻。该病可归属于中医泄泻、久痢、肠风、脏毒、腹痛等范畴。本文通过综述UC的中医病因病机及风邪与其相关性,结合“风药”在该疾病治疗中的治法、实验研究概况,重点从炎症反应、抗氧化和保护肠膜黏膜屏障等方面对近年来“风药”治疗UC的相关研究作出系统的归纳和总结,以探讨新的可能机制,为该病提供治疗策略和思路。
Ulcerative colitis(UC)is a subtype of inflammatory bowel disease,which is a chronic lifelong disease.Its clinical features mainly include recurrence and remission process,idiopathic intestinal inflammation,bloody diarrhea and weight loss.The disease can be attributed to the traditional Chinese medicine diarrhea,dysentery,intestinal wind,dirty poison,abdominal pain and other categories.This article reviews the etiology and pathogenesis of UC in traditional Chinese medicine and its correlation with wind evil,combined with the treatment and experimental research of"wind medicine"in the treatment of this disease,focusing on the inflammatory response,anti-oxidation and protection of intestinal mucosal barrier.The related research on the treatment of UC with"wind medicine"in recent years has been systematically summarized and summarized to explore new possible mechanisms and provide treatment strategies and ideas for the disease.
作者
王慧雯
冯芷菱
邬斌
江滨
WANG Huiwen;FENG Zhiling;WU Bin;JIANG Bin(Nanjing University of Chinese Medicine,Nanjing 210023;Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine,Nanjing 210006,China)
出处
《临床医学研究与实践》
2024年第12期195-198,共4页
Clinical Research and Practice
关键词
溃疡性结肠炎
风药
氧化应激
肠道屏障
ulcerative colitis
wind medicine
oxidative stress
intestinal barrier
