摘要
目的研究分析胃炎合并胃溃疡使用阿莫西林、奥美拉唑联合治疗的临床功效。方法随机选取2021年11月—2022年1月冠县新华医院收治的70例胃炎合并胃溃疡患者为研究对象,以奇偶数方式分为两组,对照组(35例)单用奥美拉唑治疗,研究组(35例)予以阿莫西林、奥美拉唑联合用药治疗,比较两组生化检验指标(胃泌素、胃动素、反应蛋白)、不良反应发生率、症状反应(嗳气、食欲减退、恶心、呕吐、腹胀、腹痛)症候积分疗效分析。结果治疗后,研究组生化检验指标均优于对照组,差异有统计学意义(P<0.05);研究组不良反应总发生率为2.85%,低于对照组的20.00%,差异有统计学意义(χ^(2)=5.081,P=0.024);治疗后,研究组症候积分低于对照组,差异有统计学意义(P<0.05);研究组预后疾病复发率低于对照组,差异有统计学意义(P<0.05)。结论阿莫西林联合奥美拉唑用药治疗胃炎合并胃溃疡,可有效改善患者病症反应,促进其胃功能恢复,缓解炎症反应,同时能够保障患者用药安全。
Objective To study and analyze the clinical efficacy of the combined treatment of gastritis combined with gastric ulcer using amoxicillin and omeprazole.Methods 70 patients with gastritis combined with gastric ulcer admitted to Xinhua Hospital of Guanxian County from November 2021 to January 2022 were randomly selected as the study objects,and they were divided into two groups in an odd-even way.The control group(35 cases)were treated with omeprazole alone,and the study group(35 cases)were treated with amoxicillin combined with omeprazole.The biochemical indicators(gastrin,motilin,reactive protein),incidence of adverse reactions,symptom reactions(belching,loss of appetite,nausea,vomiting,abdominal distension,abdominal pain)syndrome integration of the two groups were compared.Results After treatment,the biochemical indexes of the study group were better than those of the control group,and the differences were statistically significant(P<0.05).The total incidence of adverse reactions in the study group was 2.85%,lower than that in the control group(20.00%),and the difference was statistically significant(χ^(2)=5.081,P=0.024).After treatment,symptom scores of the study group were significantly lower than control group,and the differences were statistically significant(P<0.05).The prognosis incidence of disease recurrence in the study group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion Amoxicillin combined with omeprazole in the treatment of gastritis combined with gastric ulcer can effectively improve the disease response of patients,promote the recovery of gastric function,relieve inflammation,and ensure the safety of patients with medication.
作者
申兰国
SHEN Languo(Guanxian Xinhua Hospital,Liaocheng,Shandong Province,252500 China)
出处
《中外医疗》
2024年第5期115-118,共4页
China & Foreign Medical Treatment
关键词
阿莫西林
奥美拉唑
联合治疗
胃炎合并胃溃疡
临床效果
Amoxicillin
Omeprazole
Combined treatment
Gastritis combined with gastric ulcer
Clinical effect
