摘要
瘢痕疙瘩是继发于皮肤外伤或自发形成和过度生长的病理性瘢痕组织,具有增生能力强、复发率高等特点,严重影响患者的身心健康。目前的治疗方法有手术切除、皮损内注射、放射疗法,但效果常不能令人满意。光动力疗法(photodynamic therapy,PDT)是药械联合的非侵入性治疗方式,目前被广泛应用于皮肤肿瘤及多种皮肤疾病的治疗。近年来相继有临床报道PDT可有效治疗瘢痕疙瘩。本文对PDT在瘢痕疙瘩治疗中的研究进展进行综述。
Keloids are pathological scar tissue that forms and overgrows secondary to skin trauma or spontaneously,with strong proliferative ability and high recurrence rate,seriously affecting the physical and mental health of patients.Current treatments include surgical excision,intradermal injection,and radiation therapy,but the results are often unsatisfactory.Photodynamic therapy(PDT)is a non-invasive treatment modality combined with drugs and devices,which is widely used in the treatment of skin tumors and many other skin diseases.In recent years,there have been successive clinical reports that it can effectively treat keloids.This article reviews the research progress of PDT in the treatment of keloid.
作者
翟小玉
徐智怡
赵静婷
王静
谷丽
周舒
顾丽群
花卉
ZHAI Xiaoyu;XU Zhiyi;ZHAO Jingting;WANG Jing;GU Li;ZHOU Shu;GU Liqun;HUA Hui(Department of Dermatology,Nantong Third People′s Hospital,Affiliated Nantong Hospital 3 of Nantong University,Jiangsu 226006;Medical School,Nantong University)
出处
《南通大学学报（医学版）》
2024年第1期58-62,共5页
Journal of Nantong University(Medical sciences)
基金
国家自然科学基金资助项目(81903246)
南通市科技计划项目(MS22022102)
南通市卫生健康委员会科研课题(QA2021043)
南通市青年医学专家培育计划,江苏省研究生科研与实践创新计划项目(SJCX23_1804)。
关键词
瘢痕疙瘩
光动力
光动力联合治疗
keloid
photodynamic
combined photodynamic therapy
