摘要
糖尿病是以高血糖为特征的慢性代谢性疾病。根尖周炎是一种以牙周组织破坏为特征的感染性疾病,是根管系统微生物群、微生物毒性因子和宿主免疫应答之间复杂相互作用的结果。糖尿病和根尖周炎是两种生物学相关的疾病,糖尿病和根尖周炎的双向关系一直是研究的重点。本文综述了糖尿病和根尖周炎两种疾病近年来在根管治疗效果、血糖水平、炎症反应等因素之间存在的关联。深入了解糖尿病与根尖周炎之间的关系对阐明其双向机制具有重要意义,将为临床更好更准确治疗糖尿病伴根尖周炎患者产生积极影响。
Diabetes mellitus is a chronic metabolic disease characterized by hyperglycemia.Apical inflammation is an infectious disease characterized by the destruction of periodontal tissue.It is the result of complex interaction between microbiota,microbial virulence factors,and host immune response in the root canal system.Diabetes mellitus and apical inflammation are two biologically related diseases.The bidirectional relationship between diabetes and apical inflammation has been the focus of in-depth research.This article reviews the relationship between effects of root canal treatment,blood glucose level,and inflammatory response of diabetes mellitus and apical inflammation in recent years.A thorough understanding of the relationship between diabetes and apical inflammation is of great significance to elucidate the bidirectional mechanism,and will have a positive impact on better and more accurate treatment of diabetes patients with apical inflammation.
作者
刘月华
田宇
LIU Yuehua;TIAN Yu(Northwest University,Xi’an 710069,China;State Key Laboratory of Oral&Maxillofacial Reconstruction and Regeneration,National Clinical Research Center for Oral Diseases,Shaanxi Key Laboratory of Stomatology,Department of Operative Dentistry and Endodontics,School of Stomatology,the Fourth Military Medical University,Xi’an 710032,China.)
出处
《口腔医学研究》
CAS
CSCD
北大核心
2024年第4期283-286,共4页
Journal of Oral Science Research
基金
国家自然科学基金(编号:81970929)。
关键词
糖尿病
根尖周炎
根管治疗
血糖水平
diabetes mellitus
apical inflammation
root canal treatment
blood glucose level
