摘要
抑郁症是我国最常见的精神障碍之一,其认知功能障碍影响着患者的预后和生活质量,也与抑郁症高复发率有关。重复经颅磁刺激(repetitive transcranial magnetic stimulation,rTMS)是无创脑刺激技术的一种,广泛用于抑郁症的治疗,但对抑郁症患者认知功能障碍的疗效尚未得出统一结论。本文通过回顾相关文献,总结rTMS对抑郁症患者认知功能不同维度的疗效,分析其治疗相关机制及安全性,发现其可以改善抑郁症患者的部分认知维度且无认知副作用。此外,进一步归纳了精准、个体化rTMS治疗抑郁症认知障碍的最新进展,为将来开展相关临床工作和科研工作提供理论借鉴。
Depression is one of the most common mental disorders in China.Its hindrance on cognitive functioning affects not only affect the patient's quality of life and prognosis,but also links to high rates of depression recurrence.Repetitive transcranial magnetic stimulation(rTMS)is a kind of non-invasive brain stimulation technology,which is widely used in the treatment of depression.However,there is no unified conclusion on the efficacy of rTMS on cognitive dysfunction in patients with depression.By reviewing the relevant literature,this paper summarizes the efficacy of rTMS on different cognitive domains in patients with depression,and analyzes the mechanism and safety of rTMS treatment.It is found that rTMS can improve some cognitive domains in patients with depression without cognitive side effects.Additionally,this article summarizes the latest progress in precise and personalized rTMS therapy for cognitive dysfunction in depression,providing a theoretical reference for future clinical and scientific pursuits.
作者
刘念
蔡敏
唐乃龙
韩天乐
吕润欣
张裕裕
张遥迟
王化宁
LIU Nian;CAI Min;TANG Nai-long;HAN Tian-le;LYU Run-xin;ZHANG Yu-yu;ZHANG Yao-chi;WANG Hua-ning(Department of Psychiatry,First Affiliated Hospital,Air Force Medical University,Xi′an 710032,China)
出处
《临床精神医学杂志》
CAS
2024年第2期157-160,共4页
Journal of Clinical Psychiatry
基金
国家自然科学基金(81974215)
空军军医大学临床研究项目(2021XB023)。
关键词
抑郁症
认知功能障碍
经颅磁刺激
depression
cognitive dysfunction
transcranial magnetic stimulation
