摘要
目的探讨磁共振T1rho序列、T2 mapping技术在膝关节早期软骨退变早期诊断中的评估价值。方法选取2020年1月至2022年11月在我院治疗的110例膝关节早期软骨退变患者(观察组),按照疾病严重程度分为轻度退变组及重度退变组,另选取同期在我院进行体检的64例健康者为对照组,受试者均行磁共振T1rho序列、T2 mapping技术扫描,测量受试者T2值及T1ρ值,探讨磁共振T1rho序列、T2 mapping技术在膝关节早期软骨退变早期诊断中的评估价值。结果观察组股骨外侧面、股骨内侧面、胫骨外侧面、胫骨内侧面、髋骨面T2值均明显高于对照组(P<0.05),重度退变亚组患者股骨外侧面、股骨内侧面、胫骨外侧面、胫骨内侧面、髋骨面T2值显著高于轻度退变者(P<0.05);观察组股骨内踝负重区、股骨内踝非负重区、股骨外踝负重区、股骨外踝非负重区、胫骨外侧平台区、胫骨内侧平台区、髌后软骨区磁共振T1ρ值明显高于对照组(P<0.05),重度退变亚组患者股骨内踝负重区、股骨内踝非负重区、股骨外踝负重区、股骨外踝非负重区、胫骨外侧平台区、胫骨内侧平台区、髌后软骨区磁共振T1ρ值明显高于轻度退变亚组患者(P<0.05);磁共振T1rho序列在膝关节早期软骨退变中早期诊断及严重程度评估中的的诊断ROC值及特异度明显高于T2 mapping技术(P<0.05),但后者具有更高的敏感度(P<0.05)。结论磁共振T1rho序列、T2 mapping技术均能有效反映膝关节早期软骨退变中软骨组织学成分变化情况,还可为膝关节软骨退变严重程度评估提供客观依据,二者具有一定互补价值。
Objective To evaluate the value of MRI T1rho sequence and T2 mapping in the early diagnosis of early cartilage degeneration of the knee.Methods A total of 110 patients with early cartilage degeneration of knee joint treated in our hospital from January 2020 to November 2022(observation group)were selected and divided into mild degeneration group and severe degeneration group according to the severity of the disease.Another 64 healthy patients who underwent physical examination in our hospital during the same period were selected as control group.All subjects were scanned with magnetic resonance T1rho sequence and T2 mapping technology,and their T2 and T1-ρvalues were measured to explore the evaluation value of magnetic resonance T1rho sequence and T2 mapping technology in the early diagnosis of early cartilage degeneration of the knee joint.Results T2 values of lateral femur,lateral femur,lateral tibia,lateral tibia and hip bone surface in observation group were significantly higher than those in control group(P<0.05),and T2 values of lateral femur,lateral femur,lateral tibia,lateral tibia and hip bone surface in severe degeneration subgroup were significantly higher than those in mild degeneration group(P<0.05).The T1-ρvalue of magnetic resonance in loading area of medial malleolus of femur,non-loading area of medial malleolus of femur,loading area of lateral malleolus of femur,non-loading area of lateral malleolus of femur,medial tibial plateau area and posterior patellar cartilage area of observation group was significantly higher than that of control group(P<0.05).The T1-ρvalue of magnetic resonance in the weight-bearing area of medial malleolus of femur,non-weight-bearing area of medial malleolus of femur,lateral malleolus of femur,non-weight-bearing area of lateral malleolus of femur,medial tibial plateau area and posterior patellar cartilage area of patients in severe degeneration subgroup was significantly higher than that in mild degeneration subgroup(P<0.05).The diagnostic ROC value and specificity o
作者
唐毅
张辉
黄恺
黎本丰
TANG Yi;ZHANG Hui;HUANG Kai;LI Ben-feng(Department of Bone SectionⅡ,Jianyang People's Hospital,Jianyang 641400,Sichuan Province,China)
出处
《中国CT和MRI杂志》
2024年第4期163-165,共3页
Chinese Journal of CT and MRI
基金
四川省医学会骨科(尚安通)专项科研课题(2019SAT21)。
