摘要
目的:探讨血塞通联合甲磺酸倍他司汀治疗后循环缺血性眩晕患者的影响。方法:选取2022年1月至2023年6月在南京市中医院全科门诊治疗的160例后循环缺血性眩晕患者,随机将患者分为西药组和中西联合药物组,每组各纳入80例,西药组患者采用甲磺酸倍他司汀治疗,中西联合药物组采用血塞通联合甲磺酸倍他司汀治疗,两组患者均持续治疗2周。比较两组患者治疗前后临床症状采用眩晕评估评分量表(DARS)、眩晕障碍调查量表(DHI)和眩晕病临床证候评价量表评估、血液流变学包括血浆黏度(PV)、全血黏度(WVB)和全血纤维蛋白原(FIB),脑血流动力学包括左椎动脉(LVA)、右椎动脉(RVA)、基底动脉(BA)和阻力系数(RI)变化,并记录两组患者治疗期间的不良反应发生情况。结果:治疗后,中西联合药物组患者的DARS、DHI量表评分和眩晕病临床证候评价量表评分均较西药组低,差异有统计学意义(P<0.05);中西联合药物组PV、WVB和FIB水平均较西药组低,差异有统计学意义(P<0.05);中西联合药物组LVA、RVA和BA水平较西药组高,RI水平较西药组低,差异有统计学意义(P<0.05)。中西联合药物组寒战、心悸、皮疹、恶心呕吐不良反应率为10.00%,西药组为6.25%,差异无统计学意义(P>0.05)。结论:血塞通联合甲磺酸倍他司汀治疗后循环缺血性眩晕患者可以改善患者临床疗效,降低患者的血压黏稠度,并有效调节患者脑血流动力循环。
Objective:To investigate the effect of betastine mesylate in patients with circulatory ischemic vertigo.Methods:selected in January 2022-June 2023 in Nanjing Hospital general outpatient treatment of 160 patients with circulatory ischemic vertigo,patients randomly divided into western medicine and Chinese and western combination drug group,each group in 80 cases,western medicine patients,western drug group with blood,both groups of patients are continuous treatment for 2 weeks.Compare the clinical symptoms(blood rheology(DARS),vertigo scale(DHI)and DHI),including plasma viscosity(PV),whole plasma viscosity(WVB)and whole fibrinogen(FIB)(and cerebral hemodynamics(including left vertebral artery(LVA),right vertebral artery(RVA),right vertebral artery(RVA),basilar artery(BA)and resistance coefficient(RI)(change,and record the occurrence of adverse reactions during treatment in the two groups.Results:After treatment,the DARS and DHI scale score of patients with Chinese and western combination group were lower than the western medicine group,statistically significant(P<0.05);the PV,WVB and FIB levels were lower,and the difference was statistically significant(P<0.05);the LVA,RVA and BA were higher than the western medicine group,while the RI level was lower than the western medicine group,and the difference was statistically significant(P<0.05).The adverse reaction rate of chills,palpitations,rash,nausea and vomiting in chinese and western combination drug group was 10.00%,and 6.25% in western medicine group,with no significant difference(P>0.05).Conclusion:Patients with circulatory ischemic vertigo can improve clinical efficacy,reduce blood pressure viscosity,and effectively regulate cerebral hemodynamic circulation.
作者
崔阳阳
孙艳雷
刘德翠
CUI Yangyang;SUN Yanlei;LIU Decui(General Medicine Department of Nanjing Hospital of Traditional Chinese Medicine,Nanjing 210006,China)
出处
《黑龙江医药科学》
2024年第2期128-131,共4页
Heilongjiang Medicine and Pharmacy
关键词
后循环缺血性眩晕
血塞通
甲磺酸倍他司汀
posterior circulation ischemic vertigo
Xuesaitong
betastine mesylate
