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前哨淋巴结活检联合改良根治术在乳腺癌患者中的效果价值研究

Value study of the effect of SLNB plus modified radical resection on postoperative complications in breast cancer patients
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摘要 目的:探讨乳腺癌患者采取前哨淋巴结活检(sentinel lymph node biopsy,SLNB)联合改良根治术治疗效果。方法:选取南阳市中心医院接受手术治疗的86例乳腺癌疾病患者,以入院次序为分组原则,分为对照组和观察组,各43例,改良根治术作为对照组,SLNB联合改良根治术作为观察组,对比治疗后两组手术时间、术中出血量、住院时间、临床有效率、糖类抗原125(carbohydrate antigen 125,CA125)、癌胚抗原(carcinoembryonic antigen,CEA)、糖类抗原153(cancer antigens 153,CA153)水平及健康调查简表(the MOS 36-item short form health survey,SF-36)的变化。结果:观察组手术时间、术中出血量、住院时间均明显低于对照组(P<0.05);观察组临床有效率为97.67%显著高于对照组76.74%(P<0.05);观察组术后CA125、CEA、CA153水平与对照组相对比无统计学差异(P>0.05);术后观察组的SF-36量表各项分值均高于对照组(P<0.05)。结论:临床治疗乳腺癌患者时,采取SLNB联合改良根治术治疗,不仅能有效缩短手术及住院时间,降低术中出血量,还可控制术后并发症发生率,促进康复,改善生活质量。 Objective:To explore the treatment effect of sentinel lymph node biopsy(sentinel lymph node biopsy,SLNB)combined with modified radical resection in breast cancer patients.Methods:86 patients with breast cancer in Nanyang Central Hospital,Taking the order of admission as the grouping principle,That is,the control and observation groups,The number of patients in each group was 43 patients,Modified root therapy used for the control group,SLNB with modified radical treatment,The duration of surgery,intraoperative blood loss,hospital stay,and clinical effective rate glucose antigen 125(carbohydrate antigen 125,CA125),carcinoembryonic antigen(carcinoembryonic antigen,CEA),sugar antigen 153(cancer antigens 153,CA153)level and Health Survey Summary Form(the MOS 36-item short form health survey,SF-36).Results:The operation time,intraoperative blood loss,and hospital stay were significantly lower than the observation group(P<0.05);the clinical response rate was 97.67%higher than the control group 76.74%(P<0.05);there was no statistical difference between postoperative CA125,CEA,CA153 levels and the control group(P>0.05);the SF-36 score in the observation group was higher than that of the control group(P<0.05).Conclusion:In the clinical treatment of breast cancer patients,SLNB combined with modified radical resection can not only effectively shorten the operation and hospital time,reduce the amount of intraoperative bleeding,but also control the incidence of postoperative complications,promote rehabilitation and improve the quality of life.
作者 吕玉珠 叶鹏 LÜYuzhu;YE Peng(Department of Breast Surgery,Nanyang Central Hospital,Nanyang 473005,China)
出处 《黑龙江医药科学》 2024年第2期98-102,共5页 Heilongjiang Medicine and Pharmacy
关键词 前哨淋巴结活检术 改良根治术 乳腺癌 肿瘤 并发症 sentinel lymph node biopsy modified radical resection breast cancer tumor complications
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