摘要
目的探讨袖带充气高血压与单臂缺血诱导的臂间舒张压差异(dIAD)之间的关联性。方法选取2019年1月至2021年11月于南昌大学第二附属医院行冠状动脉造影的64例患者作为研究对象,根据袖带充气高血压的诊断标准分为A组(袖带充气高血压患者)与B组[非袖带充气高血压且非假性高血压(PHT)患者],每组32例。比较两组生化指标、影像学指标、内皮功能指标及血压。结果A组估算肾小球滤过率(eGFR)低于B组,差异有统计学意义(P<0.05);两组总胆固醇(TC)、甘油三酯(TG)、空腹血糖(FPG)、低密度脂蛋白胆固醇(LDL-C)水平比较差异无统计学意义。A组颈动脉内膜中层厚度大于B组,左心室舒张功能减退率高于B组,差异有统计学意义(P<0.05);两组左心室收缩末期、舒张末期内径及室间隔厚度比较差异无统计学意义。束臂前后,A组一氧化氮(NO)浓度均低于B组,内皮素(ET)浓度均高于B组,差异有统计学意义(P<0.05);束臂前后两组过氧亚硝基阴离子(ONNOO-)浓度比较差异均无统计学意义。A组袖带收缩压与腔内收缩压差值(SS)、脉压(PP)均大于B组,差异有统计学意义(P<0.05);两组袖带舒张压与腔内舒张压差值(D-D)比较差异无统计学意义。束臂前,两组dIAD比较差异无统计学意义;束臂后,A组dIAD小于B组,差异有统计学意义(P<0.05);两组束臂前后收缩压差压(sIAD)比较差异无统计学意义。结论单壁缺血诱导可减小袖带充气高血压患者的臂间舒张压差异,对诊断袖带充气高血压具有较好效果,值得临床推广应用。
Objective To explore the correlation between cuff inflation hypertension and inter arm diastolic pressure difference(dIAD)induced by single arm ischemia.Methods 64 patients who underwent coronary angiography in the Second Affiliated Hospital of Nanchang University from January 2019 to November 2021 were selected as the study subjects,and they were divided into the group A(patients with cuff inflation hypertension)and the group B(patients with non-cuff inflation hypertension and non-pseudohypertension[PHT])according to the diagnostic criteria of cuff inflation hypertension,with 32 cases in each group.Biochemical indexes,imaging indexes,endothelial function indexes blood pressure were compared between the two groups.Results The estimated glomerular filtration rate(eGFR)in the group A was lower than that in the group B,and the difference was statistically significant(P<0.05);there were no significant differences in total cholesterol(TC),triglycerides(TG),fasting plasma glucose(FPG)and low density lipoprotein cholesterol(LDL-C)between the two groups.Carotid intium-media thickness in the group A was larger than that in the group B,and left ventricular diastolic dysfunction rate was higher than that in the group B,the differences were statistically significant(P<0.05);there were no significant differences in left ventricular end-systolic and end-diastolic diameter and interventricular septal thickness between the two groups.Before and after arm binding,the concentration of nitric oxide(NO)in the group A was lower than that in the group B,and the concentration of endothelin(ET)was higher than that in the group B,the differences were statistically significant(P<0.05);there was no significant difference in peroxynitroso anion(ONNOO^(-))of the two groups before and after arm binding.The cuff systolic pressure and intracavity systolic pressure(S-S)and pulse pressure(PP)in the group A was higher than that in the group B,and the difference was statistically significant(P<0.05);while there were no significant differences in cu
作者
钟雯
李颐
王任红
周亮
夏瑶瑶
张瑜
ZHONGWen;LI Yi;WANG Renhong;ZHOU Liang;XIAYaoyao;ZHANG Yu(Department of Cardiac Intervention,the Second Affiliated Hospital of Nanchang University,Nanchang,Jiangxi,330006,China)
出处
《当代医学》
2024年第2期20-24,共5页
Contemporary Medicine
基金
江西省重点研发计划项目(20171BBG70090)。
关键词
臂间舒张压差异
袖带充气高血压
内皮功能
缺血诱导
Inter arm diastolic pressure difference
Cuff inflation hypertension
Endothelial function
Ischemia induction
