摘要
丁酸梭菌(Clostridium butyricum)是一种革兰氏阳性、呈杆状、形成孢子且严格厌氧的细菌,其能够在碳水化合物和糖的发酵过程中产生短链脂肪酸以及生物材料的前体物质(如氢气、丁醇和1,3-丙二醇),具有潜在的应用价值。在人类和动物体内,已被证明具有益生作用,在水生动物中,丁酸梭菌作为益生菌同样拥有广阔的应用前景。本文综述了丁酸梭菌在水生动物中的分离鉴定、安全性和作用机制,总结了丁酸梭菌在改善水产动物生长性能、消化率、存活率、免疫反应、抗病性和肠道结构,以及调节肠道共生菌群和代谢方面的作用,以期为丁酸梭菌在水产养殖中更好的应用提供参考。
Clostridium butyricum is a Gram-positive,rod-shaped,spore-forming,strictly anaerobic bacterium.It can produce short-chain fatty acids and precursors of biomaterials(such as hydrogen,butanol and 1,3-propanediol)during the fermentation of carbohydrates and sugars,which has potential application value.In humans and animals,it has been proven to have a probiotic effect.In aquatic animals,Clostridium butyricum also has broad prospects as a probiotic.This article reviewed the isolation,identification,safety and mechanism of action of Clostridium butyricum in aquatic animals,and also summarized the role of Clostridium butyricum in improving the growth performance,digestibility,survival rate,immune response,disease resistance and intestinal structure of aquatic animals,as well as regulating the intestinal commensal flora and metabolism,in order to provide reference for better application of Clostridium butyricum in aquaculture.
作者
陈俊祥
鲁耀鹏
张秀霞
冼健安
郑佩华
李军涛
张泽龙
郭冉
CHEN Junxiang;LU Yaopeng;ZHANG Xiuxia;XIAN Jianan;ZHENG Peihua;LI Juntao;ZHANG Zelong;GUO Ran(College of Oceanography,Hebei Agricultural University,Qinhuangdao,Hebei Province 066000,China;Institute of Tropical Biotechnology,Chinese Academy of Tropical Agricultural Sciences,Key Laboratory of Research and Utilization of Functional Components of Marine Biological Resources in Hainan Province/Key Laboratory of Protection and Utilization of Tropical Agricultural Biological Resources of Hainan Province,Hainan Academy of Tropical Agricultural Resources,Haikou,Hainan Province 571101,China)
出处
《中国饲料》
北大核心
2024年第7期88-94,共7页
China Feed
基金
海南省自然科学基金(420QN338)
中国热带农业科学院基本科研业务费专项资金(1630052019013)
海南省研究生创新科研课题(Qhys2022-127)。
关键词
益生菌
丁酸梭菌
抗病性
肠道菌群
免疫反应
probiotics
Clostridium butyricum
disease resistance
intestinal flora
immune reaction
