摘要
人类示指与环指指长比(2D∶4D)是产前性激素(雌激素/雄激素)暴露水平及敏感性的宏观标记物之一,在性别间差异明显。产前性激素暴露对出生后个体的心理特征、运动能力及多种性激素相关疾病均有影响。本研究综述了2D∶4D与男性生殖系统癌症(前列腺癌和睾丸癌)相关性的研究进展,以期为此类疾病的早期筛查提供参考信息。
The human index finger to ring finger length ratio(2D∶4D)is one of the macro markers of prenatal exposure level and sensitivity to sex hormones(estrogen/androgen),with significant gender differences.Prenatal exposure to sex hormones has an impact on postnatal mental characteristics,motor ability and a variety of sex hormone-related diseases.In this paper,the research progress on the relationship between 2D∶4D and male reproductive system cancer(prostate cancer and testicular carcinoma)were reviewed for providing reference information for early screening of such diseases.
作者
杨梦怡
牛世博
徐彧
霍正浩
陆宏
YANG Mengyi;NIU Shibo;XU Yu;HUO Zhenghao;LU Hong(School of Basic Medical Sciences,Ningxia Medical University,Yinchuan 750004,China;Key Laboratory of Fertility Preservation and Maintenance,Ministry of Education,Yinchuan 750004,China)
出处
《宁夏医科大学学报》
2024年第2期199-203,共5页
Journal of Ningxia Medical University
基金
国家自然科学基金项目(32160211,31460272)。
关键词
2D∶4D
性激素
前列腺癌
睾丸癌
2D∶4D
sex hormones
prostate cancer
testicular carcinoma
