摘要
目的:探究氨基末端脑钠肽前体(NT-proBNP)、左室射血分数(LVEF)、心电图碎裂QRS波群(fQRS)与急性心肌梗死(AMI)患者不良预后的关系。方法:采用巢式病例对照研究方法,选取2021年1月-2023年1月于河池市第三人民医院行经皮冠状动脉介入治疗(PCI)的AMI患者96例作为研究对象,依据术后6个月是否发生主要心血管不良事件进行分组,将预后不良的患者纳入预后不良组,随后在研究队列人群中按照1∶2频数配比纳入预后良好的患者为预后良好组。收集并分析患者的临床信息,采用Logistic回归模型分析NT-proBNP、LVEF及fQRS与AMI预后不良的相关性。结果:96例AMI患者术后随访6个月发现预后不良患者19例(19.78%)。多因素Logistic回归分析结果提示,NT-proBNP水平上升、LVEF降低、发生fQRS是AMI患者不良预后的影响因素(P<0.05)。结论:NT-proBNP、LVEF、fQRS是AMI患者不良预后的影响因素,在预测心血管不良事件及预后具有重要意义。
Objective:To explore the relationship between amino-terminal brain natriuretic peptide precursor(NT-proBNP),left ventricular ejection fraction(LVEF),ECG fragmentation QRS wave group(fQRS)and poor prognosis in patients with acute myocardial infarction(AMI).Methods:A nested case-control study was used to select ninty-six patients with AMI who underwent percutaneous coronary intervention(PCI)in Hechi Third People's Hospital from January 2021 to January 2023 as the study objects.According to the occurrence of major adverse cardiovascular events 6 months after surgery,patients with poor prognosis were included in the poor prognosis group,and then patients with good prognosis were included in the study cohort according to the 1∶2 frequency ratio as the good prognosis group.Clinical information of patients was collected and analyzed.Logistic regression model was used to analyze the correlation between NT-proBNP,LVEF and fQRS and poor prognosis of AMI.Results:The 96 patients with AMI were followed up 6 months after operation,19 patients(19.78%)had poor prognosis;multivariate Logistic regression analysis showed that the increase of NT-proBNP level,the decrease of LVEF and the occurrence of fQRS were the influential factors for the poor prognosis of AMI patients(P<0.05).Conclusion:The increase of NT-proBNP level,the decrease of LVEF and the occurrence of fQRS are the factors influencing the poor prognosis of AMI patients.
作者
魏苇
韦柳江
覃宏慧
兰菲菲
Wei Wei;Wei Liujiang;Qin Honghui;Lan Feifei(Department of Function,Hechi Third People's Hospital,Hechi 547000,Guangxi Zhuang Autonomous Region,China;Department of Ultrasound,Guangxi International Zhuang Medical Hospital,Nanning 530000,Guangxi Zhuang Autonomous Region,China)
出处
《中外医药研究》
2024年第3期6-8,共3页
JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH
基金
广西壮族自治区卫生健康委员会自筹经费科研课题(编号:Z-M20221856)。
关键词
急性心肌梗死
碎裂QRS波群
氨基末端脑钠肽前体
左室射血分数
心功能
心血管不良事件
Acute myocardial infarction
Fragmentation QRS group
Amino-terminal brain natriuretic peptide precursor
Left ventricular ejection fraction
Heart function
Major cardiovascular adverse events
