摘要
目的:研究孤独症谱系障碍(autism spectrum disorder,ASD)儿童的睡眠问题与其相关因素,为ASD共患睡眠问题的儿童提供防治依据。方法:选取2019年7月-2022年12月就诊于佛山市妇幼保健院儿童保健科的84例ASD儿童(ASD组),和同地区同时期84例年龄匹配的正常儿童进行对比。收集两组儿童的社会人口学资料调查表和儿童睡眠习惯问卷(children’s sleep habits questionnaire,CHSQ),通过t检验或卡方检验对两组儿童的基本情况及睡眠情况进行比较,再通过logistic回归分析模型对ASD儿童的睡眠情况相关因素进行分析。结果:ASD组儿童和对照组儿童存在睡眠问题的检出率分别为91.7%和81.0%,两者差异具有统计学意义(P≤0.05),说明ASD组的睡眠问题检出率更高。ASD组在CHSQ总分、异态睡眠、日间嗜睡方面评分高于对照组,且两组差异具有统计学意义(P值均≤0.05),说明ASD组儿童存在睡眠问题更多,特别是在异态睡眠和日间嗜睡方面。logistic分析结果显示,母亲孕期补充维生素D有益于改善ASD儿童的睡眠问题(OR=0.01,P≤0.05)。结论:ASD儿童相比于正常儿童更可能出现睡眠问题,母亲孕期是否补充维生素D可能与ASD儿童存在睡眠问题相关。
Objective:To investigate the sleep problems and related factors in children with autism spectrum disorder(ASD),so as to provide a basis for prevention and intervention of sleep problems in children with ASD.Methods:84 children with ASD were selected as ASD group by the department of child healthcare in Foshan Maternity and Child Healthcare Hospital from July 2019 to December 2022,as well as 84 typical development children with matched age in the same region and period were selected as the control group.Compare the sleep status of the children in both two groups and analyze the correlation factors by demographic data questionnaires and Children’s Sleep Habits Questionnaire(CHSQ).Independent t test and chi-square test were used to compare the general characteristics and sleep status,after that logistic regression was used to analyze the risk factors of sleep problems in ASD group.Results:The survey showed that 91.7 percent of ASD children and 81.0 percent of typical development group had sleep disorders,with statistically significant difference(P≤0.05),that meant the detection rate of sleep disorders in ASD children was higer than typical development children.ASD children had significantly higher scores than typical development children in CHSQ total scores,parasomnias and daytime sleepiness,with statistically significant difference(P≤0.05),which meant ASD children had more sleep problems than typical development children,especially in parasomnias and daytime sleepiness.Logistic analysis showed that those ASD children whose mothers had maternal Vitamin D supplement during pregnancy were more likely to decrease sleep problems(OR=0.01,P≤0.05).Conclusion:ASD children may be more likely to have sleep problems than the normal children.Maternal Vitamin D supplement during pregnancy may be the correlation factor of ASD children with sleep problems.
作者
孙若瑜
蔡晓琰
倪豪波
郭貔
SUN Ruoyu;CAI Xiaoyan;NI Haobo;GUO Pi(Department of Public Health and Preventive Medicine,Shantou University Medical College,Shantou 515041,China;Department of Child Healthcare,Foshan Maternity and Child Healthcare Hospital,Foshan 528000,China)
出处
《汕头大学医学院学报》
2024年第1期49-53,共5页
Journal of Shantou University Medical College
