摘要
功能化吲哚在许多研究领域有广泛的应用,因此旋光性吲哚衍生物的合成在有机合成中有重要的意义。催化不对称Friedel-Crafts烷基化是研究吲哚区域选择性功能化最直接、最彻底的方法。本文综述了近二十年来有机催化剂催化吲哚的不对称Friedel-Crafts烷基化反应的进展,并对此作出总结与展望。
Functionalized indoles are widely used in many research fields,so the synthesis of optically active indole derivatives is of great significance in organic synthesis.Catalytic asymmetric Friedel-Crafts alkylation is the most direct and thorough method to study the regioselective functionalization of indoles.In this paper,the progress of asymmetric Friedel-Crafts alkylation of indoles catalyzed by organic catalysts in recent 20 years is reviewed,and the summary and prospect are made.
作者
曾宣云
Zeng Xuanyun(Lanzhou Jiaotong University,Lanzhou 730070,China)
出处
《广东化工》
CAS
2024年第5期52-56,29,共6页
Guangdong Chemical Industry
