摘要
研究针对眼部抗皱,以银耳子实体提取物和铁皮石斛提取物两种天然原料为主要功效原料制备了一款眼膜。并从配方稳定性、透皮吸收性、产品安全性和产品功效性几个方面评估其特性,结果表明:该眼膜配方稳定性好,并通过体外猪皮模型证明能够透过皮肤被吸收;参照《化妆品安全技术规范》(2015版)的方法证实该眼膜不会对人体产生任何不良反应;参照《化妆品保湿功效评价指南》(QB/T 4256-2011)的方法证明使用该眼膜能够显著提高皮肤角质层水分含量;最后通过32名眼角皱纹明显的受试者使用4周后,发现该眼膜能减少皱纹数量、降低皱纹深度、皱纹面积和皱纹长度,并且得到受试者的一致好评。综上所述,该眼膜是一款安全稳定的保湿抗皱产品。
In this study,an eye mask was prepared with tremella fruiting body extract and Dendrobium officinale extract as the main effective raw materials.The properties of the eye mask were evaluated from the aspects of formula stability,transdermal absorption,product safety and product efficacy.The results showed that the formula had good stability and could be absorbed through the skin through pig skin model in vitro.Refer to the method of“Cosmetic Safety Technical Specification”(2015 edition)to confirm that the eye mask will not cause any adverse reaction to the human body;According to“Guidelines for Evaluation of Moisturizing Effect of Cosmetics”(QB/T 4256-2011),it was proved that the use of the eye mask can significantly improve the moisture content of the skin stratum corneum.Finally,32 subjects with obvious wrinkles at the corner of their eyes were used for 4 weeks,and it was found that the mask could reduce the number,depth,area and length of wrinkles,and was unanimously praised by the subjects.To sum up,the eye mask is a safe and stable moisturizing and anti-wrinkle product.
作者
石秀芹
翟文丽
鹿发展
吴迪
刘平平
安全
霍彤
Shi Xiuqin;Zhai Wenli;Lu Fazhan;Wu Di;Liu Pingping;An Quan;Huo Tong(Yunnan Baiyao Group Health Products Co.,Ltd.,Kunming 650000,China;East Asian Skin Health Research Center,Beijing 100048,China;Beijing Ruier Testing Technology Co.,Ltd.,Beijing 100048,China)
出处
《广东化工》
CAS
2024年第3期56-59,28,共5页
Guangdong Chemical Industry
关键词
眼膜
天然功效原料
稳定性
安全性
透皮吸收
补水
抗皱
eye mask
natural and effective ingredients
stability
security
transdermal absorption
moisturizing
anti-wrinkle
