摘要
目的:乳腺癌已成为威胁世界女性生命健康的重大疾病。比较分析纹身标记方法和画线标记方法在患者临床放疗时对摆位误差大小的影响。方法:选取复旦大学附属肿瘤医院放射治疗中心的39例乳腺肿瘤患者(19例画线标记,20例纹身标记)。按照放疗摆位治疗单进行体位固定后,进行EPID系统图像采集。将采集图像和模拟定位图像进行图像配准比对,记录在VER方向、LNG方向和LAT方向的平移误差值,计算其平均值,标准差,系统误差和随机误差,采用独立样本t检验比较数据差异有无统计学意义。结果:画线标记组患者在各方向上的摆位误差VER、LNG、LAT结果为(2.99±1.95)mm,(2.36±1.62)mm,(2.14±1.21)mm。纹身标记组患者在各方向的摆位误差VER、LNG、LAT结果为(2.18±1.49)mm,(1.90±1.03)mm,(1.94±1.03)mm。独立样本t检验分析显示两组VER和LNG方向误差数据差异有显著差异(P<0.05)。画线标记组较纹身标记组在各方向有更大的系统误差和随机误差。结论:纹身标记方法可使患者放疗摆位误差显著变小;可使用纹身标记方法代替画线标记方法对患者进行放疗体表标记。
Objective:Breast cancer is the major disease of threatening the health of women in the world.To compare and analyze the effects of tattoo marking and line marking on the set-up error during clinical radiotherapy.Methods:39 patients with breast cancer were selected and they were fixed according to the radiotherapy setup sheet.EPID system acquired images.The images were aligned with simulation planning CT images.These aligned results for images in VER,LNG and LAT directions for translation error were calculated to means,standard deviations,systemic error and random error.Independent sample t test was applied to evaluate the differences.Results:The set-up errors of line drawing marking patients in VER,LNG,LAT directions were(2.99±1.95)mm,(2.36±1.62)mm,(2.14±1.21)mm,respectively.The set-up errors of tattoo marking patients in VER,LNG,LAT directions were(2.18±1.49)mm,(1.90±1.03)mm,(1.94±1.03)mm,respectively.The set-up errors in VER and LNG had significant differences(P<0.05).The line marking group has greater systemic error and random error in all directions than the tattoo marking group.Conclusion:The tattoo marking method can significantly reduce the patient’s radiotherapy set-up error.The tattoo marking method can be used instead of the line marking method to mark the patient’s body surface for radiotherapy.
作者
鲁晓腾
李乾永
崔健淳
刘万阳
许青
LU Xiao-teng;LI Qian-yong;CUI Jian-chun;LIU Wan-yang;XU Qing(Department of Radiation Oncology,Fudan University Shanghai Cancer Center,Department of Oncology,Shanghai Medical College,Fudan University,Shanghai 200032)
出处
《中国医疗器械信息》
2024年第6期11-13,共3页
China Medical Device Information
关键词
乳腺癌
纹身标记
画线标记
摆位误差
breast cancer
the tattoo marking
the line marking
set-up error