摘要
多系统萎缩是一种进行性神经退行性疾病,临床表现为自主神经功能衰竭、帕金森综合征和小脑共济失调的多种组合。2022年国际运动障碍协会更新了多系统萎缩的诊断标准,“运动症状开始3年后出现严重的言语损害”是支持性运动特征之一,提示言语障碍可能成为一种新的临床标志物。本文就多系统萎缩言语障碍的研究进展作一综述。
Multiple system atrophy(MSA)is a progressive neurodegenerative disease characterized by a variety of combinations of autonomic failure,Parkinson's disease,and cerebellar ataxia.In 2022,the Movement Disorders Society updated the diagnostic criteria for MSA,which states that“severe speech impairment within 3 years of motor onset”is one of the supportive motor features,suggesting that speech impairment might be an underlying clinical marker.This paper reviews the research progress of the speech disorders in MSA.
作者
王一淳
刘恒鑫
王含
WANG Yichun;LIU Hengxin;WANG Han(Grade 202l,Chinese Academy of Medical Sciences,Peking Union Medical College Hospital,Peking Union Medical College,Beijing 100730,China;Department of Otolaryngology,Head and Neck Surgery,Beijing Children's Hospital Affiliated to Capital Medical University,Beijing Key Laboratory of Pediatric Otolaryngology and Head and Neck Surgery,Beijing 100045,China;Departmentof Neurology,Chinese Academy of Medical Sciences,Peking Union Medical College Hospital,Beijing 100730,China)
出处
《中华实用诊断与治疗杂志》
2024年第2期209-212,共4页
Journal of Chinese Practical Diagnosis and Therapy
基金
国家自然科学基金(82171255)。
关键词
多系统萎缩
言语障碍
神经退行性疾病
multiple system atrophy
speech disorder
neurodegenerative disease
