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间隙性压力治疗系统对乳腺癌术后下肢深静脉血栓形成的预防效果

The Preventive Effect of Intermittent Pneumatic Compression Therapy System on Postoperative Lower Limb Deep Vein Thrombosis in Breast Cancer Patients
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摘要 目的探讨间隙性压力治疗系统对乳腺癌术后下肢深静脉血栓形成(DVT)的预防作用。方法选择2020年5月至2022年6月于医院行乳腺癌根治术后患者120例,根据治疗方法不同,分为对照组与试验组,每组60例。对照组予踝泵运动治疗,试验组在对照组基础上采用间隙性压力治疗系统治疗,两组治疗均>7 d。比较两组下肢血流动力学指标(股静脉和足背静脉血流速度)、凝血功能指标[血清活化部分凝血活酶时间(APTT)和D-二聚体]、术后7 d内DVT发生情况。结果治疗后3 d,两组下肢股静脉和足背静脉血流速度快于治疗前,且试验组快于对照组,差异有统计学意义(P<0.05)。治疗后3 d,两组血清APTT水平较治疗前上升,D-二聚体水平较治疗前下降,差异有统计学意义(P<0.05),且试验组血清APTT水平高于对照组,D-二聚体水平低于对照组,差异有统计学意义(P<0.05)。治疗后7 d内,试验组DVT发生率低于对照组,差异有统计学意义(P<0.05)。结论间隙性压力治疗系统用于乳腺癌术后,不仅可加快股静脉和足背静脉血流速度,改善下肢血流动力学指标,且可改善凝血功能,降低下肢DVT的发生率。 Objective To investigate the preventive effect of intermittent pneumatic compression therapy system on postoperative lower limb deep vein thrombosis(DVT)in breast cancer patients.Methods A total of 120 patients who underwent breast cancer radical surgery from May 2020 to June 2022 were selected according to different treatment nethods,and divided into control group and experimental group.The conventional group received ankle pump exercise therapy,while the experimental group received intermittent pneumatic compression therapy system in addition to ankle pump exercise therapy.The treatment duration for both groups was more than 7 days.The lower limb hemodynamic parameters(femoral vein and dorsalis pedis vein blood flow velocity),coagulation function indicators(activated partial thromboplastin time[APTT]and D-dimer),and the occurrence of DVT within 7 days after surgery were compared between the two groups.Results After 3 days of treatment,the blood flow velocity of the femoral vein and dorsalis pedis vein in both groups was faster than before treatment,and the experimental group was faster than theconventional group,with signifiant significance(P<0.05).After 3 days of treatment,the serum APTT level increased and the D-dimer level decreased in both groups compared to before treatment,with signifiant significance(P<0.05),and the serum APTT level in the experimental group was higher and the D-dimer level was lower than that in theconventional group,with signifiant significance(P<0.05).Within 7 days after treatment,the incidence of DVT in the experimental group was lower than that in theconventional group,with signifiant significance(P<0.05).Conclusion The use of intermittent pneumatic compression therapy system after breast cancer surgery can not only accelerate the blood flow velocity of the femoral vein and dorsalis pedis vein,improve lower limb hemodynamic parameters,but also improve coagulation function and reduce the incidence of lower limb DVT.
作者 任霞 陈黎黎 Ren Xia;Chen Lili(Zhejiang Taizhou Hospital,Taizhou Zhejiang 318050,China)
机构地区 浙江省台州医院
出处 《医疗装备》 2024年第5期16-18,23,共4页 Medical Equipment
关键词 乳腺癌 间隙性压力治疗系统 血流动力学 凝血功能 下肢深静脉血栓形成 Breast cancer Intermittent pneumatic compression therapy system Hemodynamics Coagulation function Lower limb deep vein thrombosis
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