摘要
目的:系统检索并总结非酒精性脂肪性肝病(NAFLD)减重管理的最佳证据,为NAFLD患者的临床减重管理提供循证学参考。方法:采用文献循证研究的方法,依据PIPOST模型,对国内外相关的专业数据库的证据级别由高到低进行逐层检索,最后由2名独立的研究员对检索到的文献进行纳排、质量评价和证据提取,总结出NAFLD患者减重管理的最佳证据。结果:通过系统的证据检索,共纳入文献28篇,其中指南11篇,系统评价12篇,专家共识5篇。共总结出9个方面主题32条最佳证据,主题分别为纳入人群范围、评估与筛查、多学科团队、管理目标、饮食干预、运动干预、中医干预、行为干预、监测及随访。结论:通过总结NAFLD患者减重管理最佳证据,为NAFLD患者减重管理方案的制定提供了循证学依据,并为NAFLD患者临床减重管理的开展提供参考。
Objective:To systematically search and summarize the best evidence of weight loss management in patients with non-alcoholic fatty liver disease(NAFLD),and to provide evidence-based reference for clinical weight loss management in patients with NAFLD.Methods:The method of evidence-based literature research and PIPOST model were used to search the evidence level from high to low in relevant professional databases at home and abroad.Finally,two independent researchers conducted the sorting,quality evaluation,and evidence extraction of the retrieved literature,and finally summarized the best evidence for the management of weight loss in NAFLD patients.Results:A total of 28 kinds of literature was included through systematic evidence search,including 11 guidelines,12 systematic reviews,and five expert consensus articles.In total,32 pieces of best evidence were obtained from nine subjects,including population inclusion,assessment and screening,multidisciplinary teams,management goals,diet intervention,exercise intervention,traditional Chinese medicine intervention,behavioral intervention,monitoring,and follow-up.Conclusion:By summarizing the best evidence of weight loss management in patients with NAFLD,evidence-based evidence can be provided for the formulation of weight loss management programs in patients with NAFLD,and reference and guidance can be provided for clinical weight loss management in patients with NAFLD.
作者
姜昊
熊振芳
李芷涵
丁琳琳
张小娜
JIANG Hao;XIONG Zhen-fang;LI Zhi-han(Zhongnan Hospital of Wuhan University(Wuhan,430071),China)
出处
《中西医结合肝病杂志》
CAS
2024年第3期242-249,共8页
Chinese Journal of Integrated Traditional and Western Medicine on Liver Diseases
基金
湖北省卫健委中医药科研项目基金(No.ZY2021M024)。
