摘要
目的研究奥卡西平治疗方案用于原发性三叉神经痛疾病当中的临床价值。方法选取2022年3月—2023年3月菏泽市第三人民医院收治的60例原发性三叉神经痛疾病患者为研究对象,根据治疗方案的不同分为对照组和研究组,各30例。对照组接受卡马西平治疗,研究组接受奥卡西平治疗,比较两组治疗效果、疼痛评分、不良反应发生情况。结果研究组治疗有效率(96.67%)高于对照组(76.67%),差异有统计学意义(χ^(2)=5.192,P<0.05);治疗前,两组疼痛评分比较,差异无统计学意义(P>0.05);经治疗4周以及8周后研究组疼痛评分低于对照组,差异有统计学意义(P均<0.05);研究组不良反应发生率(3.33%)低于对照组(33.33%),差异有统计学意义(P<0.05)。结论治疗原发性三叉神经痛患者时采用奥卡西平药物,不仅可快速舒缓患者的疼痛,同时也会提高疾病治疗的效果,用药安全性值得保障。
Objective To study the clinical value of oxcarbazepine treatment program in primary trigeminal neuralgia.Methods A total of 60 patients with primary trigeminal neuralgia admitted to the Third People′s Hospital of Heze from March 2022 to March 2023 were selected as the research objects.According to the different treatment plans,they were divided into the control group and the study group,with 30 cases in each group.The control group was treated with carbamazepine,and the study group was treated with oxcarbazepine.The treatment effect,pain score,and adverse reactions were compared between the two groups.Results The effective rate of the study group(96.67%)was higher than that of the control group(76.67%),and the difference was statistically significant(χ^(2)=5.192,P<0.05).Before treatment,there was no statistically significant difference in pain scores between the two groups(P>0.05).After 4 weeks and 8 weeks of treatment,the pain scores of the study group were lower than those of the control group,and the differences were statistically significant(both P<0.05).The incidence of adverse reactions in the study group(3.33%)was lower than that in the control group(33.33%),and the difference was statistically significant(P<0.05).Conclu⁃sion The use of oxcarbazepine in the treatment of primary trigeminal neuralgia can not only quickly relieve the pain of patients,but also improve the effect of disease treatment,and the safety of the drug is worth guaranteeing.
作者
高山
石光男
张莎莎
GAO Shan;SHI Guangnan;ZHANG Shasha(Department of Neurology,Heze Third People′s Hospital,Heze,Shandong Province,274000 China;Department of Neurology,Yutian County Hospital,Tangshan,Hebei Province,064100 China)
出处
《系统医学》
2024年第1期109-111,119,共4页
Systems Medicine
关键词
原发性三叉神经痛
奥卡西平
治疗
有效性
Primary trigeminal neuralgia
Oxcarbazepine
Treatment
Effectiveness
