摘要
目的探讨雷米普利联合卡维地洛治疗心力衰竭合并心律失常的效果及对血清肌钙蛋白I(Troponin I,cTnI)、N-端前体脑钠肽(N-terminal Pro-B-type Natriuretic Peptide,NT-pro BNP)水平的影响研究。方法选取2021年6月—2023年6月肥西县中医院收治的心力衰竭合并心律失常80例患者,按照随机数表法分为研究组与对照组,各40例。对照组采用雷米普利治疗,研究组采用雷米普利联合卡维地洛治疗。对比两组的临床疗效及血清cTnI、NT-pro BNP水平。结果研究组总有效率(95.00%)高于对照组总有效率(70.00%),差异有统计学意义(χ^(2)=8.658,P<0.05);治疗后,研究组的血清cTnI、NT-pro BNP水平均低于对照组,差异有统计学意义(P均<0.05)。结论心力衰竭合并心律失常患者应用雷米普利联合卡维地洛进行治疗,能有效降低血清cTnI、NT-pro BNP水平,治疗效果显著。
Objective To investigate the effect of ramipril combined with carvedilol in the treatment of heart failure combined with arrhythmia and the effect on serum troponinⅠ(cTnI)and N-terminal pro-B-type natriuretic peptide(NT-pro BNP)levels.Methods A total of 80 patients with heart failure complicated with arrhythmia admitted to Feixi County Hospital of Traditional Chinese Medicine from June 2021 to June 2023 were selected and divided into study group and control group according to random number table method,with 40 patients in each group.The control group was treated with ramipril,and the study group was treated with ramipril combined with carvedilol.The clinical efficacy and serum levels of cTnI and NT-pro BNP were compared between the two groups.Results The total effective rate of the study group(95.00%)was higher than that of the control group(70.00%),and the difference was statistically significant(χ^(2)=8.658,P<0.05).After treatment,the serum levels of cTnI and NT-pro BNP in the study group were lower than those in the control group,and the differences were statistically significant(both P<0.05).Conclusion The application of ramipril combined with carvedilol in the treatment of patients with heart failure combined with arrhythmia can effectively reduce the levels of serum cTnI and NT-pro BNP,and the therapeutic effect is remarkable.
作者
孙荣军
SUN Rongjun(Department of Internal MedicineⅠ,Feixi County Hospital of Traditional Chinese Medicine,Hefei,Anhui Province,231200 China)
出处
《系统医学》
2024年第1期106-108,共3页
Systems Medicine
