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螺旋采集改善SPECT定量准确性及图像质量:体模研究

SwiftScan mode for improving SPECT quantitative accuracy and image quality: A phantom study
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摘要 目的观察螺旋采集用于改善SPECT定量准确性及图像质量的价值。方法针对1个包含6个球体(直径分别为37、28、22、17、13和10 mm)的体模模型,分别向球体及体模腔内灌注640 kBq/ml及20 kBq/ml^(99)Tc^(m)O_(4)^(-)溶液,并以5、10及15秒/帧行螺旋采集与常规步进采集;比较2种采集方式所获图像质量主观评分及客观参数,包括本底变异系数(CV)、对比度噪声比(CNR)、平均放射性计数(C_(sphere))和测量定量误差百分比(Error%)的差异。结果各采集时间下,螺旋采集图像质量评分均高于常规步进采集,以5秒/帧时二者差值最大;螺旋采集的CV、CNR、C_(sphere)均优于常规步进采集(P均<0.05)。排除直径10、13 mm球体后,5、10秒/帧下,螺旋采集Error%均优于常规步进采集(P均<0.05),而15秒/帧下二者差异无统计学意义(P均>0.05)。结论相同采集时间、尤其较短采集时间下,以螺旋采集所获SPECT的定量准确性及图像质量优于常规步进采集。 Objective To observe the value of Swift Scan mode for improving quantitative accuracy and image quality of SPECT.Methods A phantom model consisting 6 spheres(with diameter of 37,28,22,17,13 and 10 mm,respectively)was used,and 640 kBq/ml and 20 kBq/ml ^(99)Tc^(m)O_(4)^(-) solution were perfused into the spheres and the phantom cavity,respectively.SwiftScan mode and conventional step and shoot mode SPECT images were acquired under 5,10 and 15 s/frame,respectively.The subjective imaging quality scores,and objective indexes of imaging quality,including coefficient of variation(CV),contrast-to-noise ratio(CNR),counts sphere(C_(sphere))and measurement quantification error percentage(Error%)were compared between different modes.Results Under 5,10 and 15 s/frame,the subjective imaging quality scores of SwiftScan mode were all higher than those of conventional step and shoot mode,and the maximum difference existed under 5 s/frame.Meanwhile,CV,CNR and C_(sphere) of SwiftScan mode SPECT images were all better than those of conventional step and shoot mode under 5,10 and 15 s/frame(all P<0.05).After excluding spheres with diameters of 10 mm and 13 mm,the Error%of SwiftScan mode SPECT images were better than that of conventional step and shoot mode under 5 s/frame and 10 s/frame(all P<0.05),but no significant difference was found between 2 modes under 15 s/frame(all P>0.05).Conclusion Under the same scanning time,especially short scanning time,the quantitative accuracy and imaging quality of SwiftScan mode SPECT were both better than those of conventional step and shoot mode SPECT images.
作者 宋国庆 马成皓 杨双臣 杨鑫 张新超 田丛娜 胡玉敬 秦亚楠 魏强 边艳珠 SONG Guoqing;MA Chenghao;YANG Shuangchen;YANG Xin;ZHANG Xinchao;TIAN Congna;HU Yujing;QIN Yanan;WEI Qiang;BIAN Yanzhu(Department of Nuclear Medicine,Hebei General Hospital,Shijiazhuang 050051,China;Hebei Provincial Key Laboratory of Cerebral Networks and Cognitive Disorders,Shijiazhuang 050051,China;Department of Imaging,Shijiazhuang People's Hospital,Shijiazhuang 050011,China)
出处 《中国医学影像技术》 CSCD 北大核心 2024年第3期446-450,共5页 Chinese Journal of Medical Imaging Technology
基金 河北省卫生健康委医学科学研究课题计划(20241560、20242327)。
关键词 体层摄影术 发射型计算机 单光子 体模 显像术 定量 图像质量 tomography,emission computed,single photon phantoms,imaging quantification image quality
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