摘要
肠道内的微生物群在维持肠道健康方面起着至关重要的作用。微生物表观遗传修饰包括DNA甲基化、组蛋白修饰、染色质重塑等。本文综述了环境因素对肠道微生物群、表观遗传修饰及其在肠道微生物和相关癌症发病过程中DNA甲基化领域的研究成果,对利用肠道微生物治疗相关癌症有一定的参考价值。
The gut microbiota plays a crucial role in maintaining gut health.Microbial epigenetic modifications include DNA methylation,histone modification,chromatin remodeling etc.This article reviews the research progress in the field of environmental factors affecting gut microbiota,epigenetic modifications,and DNA methylation in gut microbiota and related cancer pathogenesis,which has certain reference value for the use of intestinal microbiota in the treatment of diseases.
作者
龚静
GONG Jing(College of Agroforestry and Health,The Open University of Sichuan,Chengdu 610073,China)
出处
《生物化工》
CAS
2024年第1期213-215,共3页
Biological Chemical Engineering
关键词
DNA甲基化
肠道微生物
肠道疾病
基因组学
DNA methylation
intestinal microorganism
intestinal diseases
genomics