摘要
Colorectal cancer(CRC),one of the most common malignant diseases,ranks second in morbidity and third in mortality among all cancers worldwide1.The liver is the most common site of distant metastasis in CRC.Liver metastasis is also the main cause of death in patients with CRC.Approximately 25%of patients with CRC have liver metastasis detected at the initial diagnosis,and approximately 50%of patients eventually develop liver metastasis during disease progression.Liver metastasis severely affects the prognosis of patients with CRC.
基金
supported by the National Natural Science Foundation of China (Grant No.82072678)
the Shanghai Science and Technology Committee Project (Grant No.23JC1401300)。
