摘要
目的探讨超微血管显像(SMI)在乳腺癌早期诊断、病情判断及疗效评估中的价值。方法选取我院2020年4月至2022年3月收治的92例乳腺癌患者作为恶性组,另选取同期114例良性乳腺结节患者作为良性组,均行SMI检查,统计对比两组的血流状况。结果良性组的血流状况明显优于恶性组(P<0.05)。受试者工作特征(ROC)曲线显示,SMI血流状况诊断乳腺癌的曲线下面积(AUC)为0.863(95%CI 0.809~0.907),最佳诊断灵敏度为84.78%,最佳诊断特异度为77.19%,截断值为Adler分级≥1级,约登指数为0.620。无淋巴结转移患者的血流状况优于有淋巴结转移患者,Ⅰ级+Ⅱ级组织分级患者的血流状况优于Ⅲ级组织分级患者(P<0.05)。相关性分析显示,SMI血流状况与淋巴结转移、组织分级呈正相关(P<0.05)。有效患者的血流状况优于无效患者(P<0.05)。结论SMI技术可为乳腺癌的临床早期诊断、病情判断、疗效评估提供参考依据,便于临床制定针对性治疗方案。
Objective To explore the value of superb microvascular imaging(SMI)in early diagnosis,disease judgment and efficacy evaluation of breast cancer.Methods A total of 92 patients with breast cancer admitted in our hospital from April 2020 to March 2022 were selected as malignant group,and 114 patients with benign breast nodules at the same period were selected as benign group.All patients underwent SMI examination,and the blood flow status of the two groups were statistically compared.Results The blood flow status of the benign group was significantly better than that of the malignant group(P<0.05).The receiver operating characteristic(ROC)curve showed that the area under curve(AUC)of SMI blood flow status in the diagnosis of breast cancer was 0.863(95%CI 0.809-0.907),the best diagnostic sensitivity was 84.78%,the best diagnostic specificity was 77.19%,the cutoff value was Adler grade≥1,and the Youden index was 0.620.The blood flow status of patients without lymph node metastasis was better than that of patients with lymph node metastasis,and the blood flow status of patients with gradeⅠ+Ⅱtissue classification was better than that of patients with gradeⅢtissue classification(P<0.05).Correlation analysis showed that SMI blood flow status was positively correlated with lymph node metastasis and tissue grade(P<0.05).The blood flow status of effective patients was better than that of ineffective patients(P<0.05).Conclusion SMI technology can provide references for early clinical diagnosis,disease judgment and efficacy evaluation of breast cancer,and facilitate the formulation of clinical targeted treatment.
作者
付饶
FU Rao(Ultrasound Department,the People's Hospital of Anyang City,Anyang 455000,China)
出处
《临床医学研究与实践》
2024年第9期109-112,共4页
Clinical Research and Practice
关键词
乳腺癌
超微血管显像
血流状况
breast cancer
superb microvascular imaging
blood flow status
