摘要
目的分析益生菌强化肠内营养结合饮食指导对老年胃疾病术后胃肠功能康复的影响。方法回顾性分析我院2021年3月—2022年3月临床收治的手术治疗的88例老年胃肠疾病患者。根据术后营养治疗方式对患者进行分组,采用常规营养治疗的40例患者纳入对照组,采用益生菌强化肠内营养的48例患者纳入研究组。比较两组患者的营养指标白蛋白(ALB)、前白蛋白(PAB)和总蛋白(TP)水平、胃肠反应发生情况、康复时间和双歧杆菌、乳酸杆菌及肠球菌等肠道菌群的数量。结果治疗前,两组ALB、PAB和TP水平的差异无统计学意义(P>0.05)。治疗4周后,患者ALB、PAB和TP水平均上升,但研究组的这3个指标均高于对照组(P<0.05)。研究组患者胃肠道发生反酸、腹胀和便秘等胃肠道反应的总发生率为6.3%,低于对照组的22.5%,组间差异具有统计学意义(P<0.05)。研究组术后肠鸣音恢复时间、首次排气时间、首次排便时间及住院时间均短于对照组,组间差异具有统计学意义(P<0.05)。治疗前,两组肠道菌群无差异(P>0.05);治疗后,研究组患者肠道双歧杆菌和乳酸杆菌数量高于对照组,肠球菌数量低于对照组,组间差异具有统计学意义(P<0.05)。结论益生菌强化肠内营养结合饮食指导能显著提高老年胃肠疾病患者术后的营养水平和胃肠功能,改善患者肠道菌群,缩短患者预后时间。
Objective To observe the effect of probiotics-fortified enteral nutrition(PFEN)combined with dietary guidance on the rehabilitation of gastrointestinal function in elderly patients after gastrointestinal disease operation.Methods A retrospective analysis was performed on 88 elderly patients with gastrointestinal diseases who underwent surgery in our hospital from March 2021 to March 2022.The patients were divided into groups according to the way of postoperative nutritional treatment.Forty patients receiving conventional nutritional treatment were included in the control group,while 48 patients receiving PFEN were included in the observation group.The levels of albumin(ALB),prealbumin(PAB)and total protein(TP),the occurrence of gastrointestinal reactions,recovery time and the counts of intestinal flora such as bifidobacterium,lactobacillus and enterococcus were compared between the two groups.Results Before treatment,there were no significant differences in ALB,PAB and TP levels between the two groups(P>0.05).After 4 weeks of treatment,the levels of ALB,PAB and TP increased,but these three indexes in the observation group were high-er than those in the control group(P<0.05).The total incidence of gastrointestinal reactions such as acid reflux,bloating and constipation in the observation group was 6.3%,lower than the 22.5%in the control group,with statistically significant difference(P<0.05);the time to recovery,time to first exhaust,time to first defecation and hospital stay after surgery were shorter than those in the control group,and the difference between groups was statistically significant(P<0.05).Before treatment,there was no difference in intestinal flora between the two groups(P>0.05).After treatment,the counts of intestinal bifidobacterium and lactobacillus in the observation group were higher,and the count of enterococcus was lower than those in the control group respectively,with statistical significances(P<0.05).Conclusion Probiotics combined with dietary guidance can significantly improve the nutrit
作者
刘伟
王艳
张永刚
房绍馨
于洋
陈占峰
徐衍杰
LIU Wei;WANG Yan;ZHANG Yonggang;FANG Shaoxin;YU Yang;CHEN Zhanfeng;XU Yanjie(General Surgery,Rizhao People's Hospital,Rizhao,Shandong 276800,China;不详)
出处
《中国微生态学杂志》
CAS
CSCD
北大核心
2024年第1期80-84,共5页
Chinese Journal of Microecology
基金
山东省医药卫生科技发展计划项目(202204010899)。
关键词
益生菌强化
肠内营养
老年
胃肠疾病患
肠胃功能康复
Probiotic enhancement
Enteral nutrition
Elderly
Gastrointestinal disease
Gastrointestinal function rehabilitation
