摘要
目的探讨数字减影血管造影(DSA)引导下经皮注射泡沫硬化剂治疗肢体静脉畸形的疗效及并发症处理。方法收集2019年6月至2021年8月暨南大学附属第一医院就诊的55例肢体静脉畸形患者的临床资料,均在DSA引导下行硬化治疗,观察术后瘤体大小变化、临床症状改善情况及并发症发生率,总结并发症的处理方案和预后情况。结果55例患者共进行了127次治疗,中位2次。治疗前后数字疼痛分级法(NRS)疼痛评分比较,差异有统计学意义(P﹤0.05)。治疗有效率为92.7%,术后出现术区肿胀、疼痛7例(12.7%),发热2例(3.6%),轻度过敏2例(3.6%),神经压迫症状2例(3.6%),1例(1.8%)肢体急性缺血症状,经积极治疗后均未发生正常组织和器官坏死、重要器官功能丧失、心肺衰竭等严重并发症。结论在DSA引导下经皮注射泡沫硬化剂治疗肢体静脉畸形安全有效,但其并发症需受到重视,尽早干预有利于减少严重不良事件的发生。
Objective To investigate the efficacy and complication of digital subtraction angiography(DSA)guided percutaneous injection of sclerosing foam in the treatment of extremity venous malformation.Method Clinical data of 55 patients with extremity venous malformation treated in the First Affiliated Hospital of Ji'nan University from June 2019 to August 2021 were collected.All patients were treated with sclerosis under the guidance of DSA.Postoperative changes in tumor size,improvement of clinical symptoms and incidence of complication were observed,and the treatment plan and prognosis of complications were summarized.Result A total of 127 treatments were performed on 55 patients,median of 2 treatments.The comparison of pain scores using the numerical rating scale(NRS)before and after treatment showed the statistically significant difference(P<0.05).The effective rate of treatment was 92.7%.After surgery,there were 7(12.7%)cases of swelling and pain in the surgical area,2 cases(3.6%)of fever,2 cases(3.6%)of mild allergies,2 cases(3.6%)of nerve compression symptoms,and 1 case(1.8%)of acute extremity ischemia symptoms,after active treatment,there were no serious complication such as normal tissue and organ necrosis,loss of important organ function,and cardiopulmonary failure.Conclusion Percutaneous injection of sclerosing foam under DSA guidance is safe and effective in the treatment of extremity venous malformation,but its complications need to be paid attention to,and early intervention is conducive to reducing the occurrence of serious adverse events.
作者
伍思意
张艳
林印胜
刘玉龙
李王海
韩键
李承志
Wu Siyi;Zhang Yan;Lin Yinsheng;Liu Yulong;Li Wanghai;Han Jian;Li Chengzhi(Department of Interventional Radiology and Vascular Surgery,the First Affiliated Hospital of Ji'nan University,Guangzhou 510630,Guangdong,China)
出处
《血管与腔内血管外科杂志》
2024年第1期51-55,共5页
Journal of Vascular and Endovascular Surgery
关键词
肢体静脉畸形
泡沫硬化剂
硬化治疗
并发症
疗效
extremity venous malformation
sclerosing foam
sclerotherapy
complication
effect
