摘要
马尔尼菲篮状菌是一种地方性机会致病真菌,主要流行于东南亚国家及中国南部。近年来,马尔尼菲篮状菌感染的发病率不断增加,在儿童中多见于免疫出生错误者。马尔尼菲篮状菌主要通过呼吸道入侵人体,感染可累及全身多组织器官,最常见的是肺部受累。儿童马尔尼菲篮状菌感染缺乏特异性的临床表现,易导致误诊或诊断延迟,病死率高。该文主要介绍马尔尼菲篮状菌及其感染的致病机制、临床特点、诊断和治疗进展。
Talaromyces marneffei is an endemic opportunistic pathogenic fungus,mainly prevalent in Southeast Asia and southern China.Recently,the morbidity of talaromyces marneffei infection has been increasing,and most are inborn errors of immunity among children.Talaromyces marneffei mainly invades human body through the respiratory tract,which can involve multiple tissues and organs,and most commonly infects the lung.The lack of specific clinical manifestations lead to misdiagnosis or delayed diagnosis and high mortality.This article mainly introduces the talaromyces marneffei and the pathogenic mechanism,clinical characteristics,and the progress in diagnosis and treatment of its infection.
作者
徐雪花
卢根
XU Xuehua;LU Gen(Department of Respiratory,Guangzhou Women and Children's Medical Center,Guangzhou Medical University,Guangzhou 510623,China)
出处
《中国实用儿科杂志》
CSCD
北大核心
2024年第2期107-111,160,共6页
Chinese Journal of Practical Pediatrics
关键词
马尔尼菲篮状菌
儿童
肺部
诊治
talaromyces marneffei
child
pulmonary
diagn-osis and treatment
