摘要
针对基于光学或荧光传感原理开发的微颗粒计数常规技术存在需对样品预处理、无法实时检测或无法精确识别微颗粒大小等问题,基于电磁感应原理,采用微型平面线圈提出了一种微颗粒识别计数传感器,可在无需预处理的情况下对不同材质及尺寸的微颗粒进行精确识别与实时计数,实验选用了钢、铜及铝3种材质及粒径范围为250~1000μm的金属微球进行测试,检测结果表明,开发的微颗粒计数传感器具有精确识别与计数能力。有望为细胞定量封装、药物定量输送、工业微颗粒检测等应用提供一种新的技术方案。
Aiming at the problem of sample pretreatment is required,unable to detect in real-time,or unable to accurately identify the size of microparticles,that conventional techniques for microparticles counting developed based on principle of optical or fluorescence sensing have,based on the principle of electromagnetic induction,a microparticle identification and counting sensor is proposed by using the microplanar coil,which can accurately identify and count microparticles of different materials and sizes in real-time without preprocessing.In the experiment,metal microspheres made of steel,copper and aluminum with the particle size range of 250~1000μm are selected for testing.The test results show that the developed sensor has accurate identification and counting ability,which is expected to provide a new technical solution for applications such as quantitative cell encapsulation,quantitative drug delivery,and industrial microparticle detection.
作者
周克佳
张玉东
邱京江
齐国臣
豆帅威
卫荣汉
ZHOU Kejia;ZHANG Yudong;QIU Jingjiang;QI Guochen;DOU Shuaiwei;WEI Ronghan(School of Mechanics and Safety Engineering,Zhengzhou University,Zhengzhou 450001,China;Institute of Intelligent Sensing,Zhengzhou University,Zhengzhou 450001,China)
出处
《传感器与微系统》
CSCD
北大核心
2024年第3期71-75,共5页
Transducer and Microsystem Technologies
基金
中国博士后科学基金资助项目(2019M662521)
国家自然科学基金青年科学基金资助项目(12102397)
河南省高等学校重点科研项目(20A460022)
河南省博士后基金资助项目(201901011)
国家自然科学基金面上资助项目(52171193)。
