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无创高频通气模式对支气管肺发育不良治疗效果的临床研究

Clinical Study on the Therapeutic Effect of Non-invasive High-frequency Ventilation Mode on Bronchopulmonary Dysplasia
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摘要 目的探讨分析无创高频通气模式对支气管肺发育不良的治疗效果。方法选取62例支气管肺发育不良患儿随机分为研究组和对照组,对照组给予常频呼吸机通气治疗,研究组给予无创高频通气治疗,比较两组患儿氧暴露时间及呼吸机使用时间,治疗前、治疗后1、2、3、4、5、6、7dOI、血气分析指标水平。结果研究组氧暴露时间及呼吸机使用时间较对照组患儿显著缩短(P<0.05),治疗前两组患儿OI指标水平差异无统计学意义(P>0.05),治疗后1、2、3、4、5、6、7d两组患儿OI指标水平均呈现上升趋势,且治疗后3、4、5、6、7d研究组患儿OI指标水平显著高于对照组患儿(P<0.05),治疗前两组患儿血气分析指标(PaO_(2)、PaCO_(2))水平差异无统计学意义(P>0.05),治疗后1、2、3、4、5、6、7两组患儿PaO_(2)指标水平均呈现上升趋势,PaCO_(2)指标水平均呈现下降趋势,且治疗后3d、4d、5d、6d、7d研究组患儿指标水平显著高于对照组,指标水平显著低于对照组患儿(P<0.05)。结论无创高频通气模式治疗BPD患儿可提高临床治疗效果,缩短氧暴露时间及呼吸机使用时间,改善氧合,促进血气分析改善,值得推广。 Objective To explore and analyze the therapeutic effect of non-invasive high-frequency ventilation mode on bronchopulmonary dysplasia;Methods Select 62 children with bronchopulmonary dysplasia were randomly divided into a study group and a control group,the control group was given constant-frequency ventilator ventilation,and the study group was given non-invasive high-frequency ventilation.The oxygen exposure time and ventilator use time were compared between the two groups before treatment,1d,2d,3d,4d,5d,and 6d after treatment,7dOI and blood gas analysis index levels;Results The oxygen exposure time and ventilator use time of the children in the study group were significantly shorter than those in the control group(P<0.05),and there was no significant difference in the levels of OI indexes between the two groups before treatment(P>0.05),the OI index levels of the children in the two groups showed an upward trend 1d,2d,3d,4d,5d,6d,and 7d after treatment,and the OI index levels of the children in the study group 3d,4d,5d,6d,and 7d after treatment were significantly higher than those in the control group(P<0.05),and there was no significant difference in the levels of blood gas analysis indexes(PaO_(2) and PaCO_(2))between the two groups before treatment(P>0.05).On 6d and 7d,the PaO_(2) index levels of the children in the two groups showed an upward trend,and the PaCO_(2) index levels showed a downward trend,and the index levels of the children in the study group were significantly higher than those in the control group on 3d,4d,5d,6d,and 7d after treatment,and the index levels were significantly higher.lower than that in the control group(P<0.05);Conclusion Non-invasive high-frequency ventilation mode in the treatment of BPD children can improve the clinical treatment effect,shorten the oxygen exposure time and ventilator use time,improve oxygenation,and promote the improvement of blood gas analysis,which is worthy of promotion.
作者 何少婷 林洪全 吴春燕 He Shaoting;Lin Hongquan;Wu Chunyan(Maoming Municipal Maternity and Infant Health Institute,Maoming 525000,China)
出处 《哈尔滨医药》 2024年第1期86-88,共3页 Harbin Medical Journal
基金 茂名市科技计划项目(210323184550723)。
关键词 无创高频通气 支气管肺发育不良 血气分析 机械通气 non-invasive high-frequency ventilation bronchopulmonary dysplasia blood gas analysis mechanical ventilation
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