摘要
动脉粥样硬化归属于中医学“脉痹”的范畴,寒邪是其重要病因之一。寒性凝滞收引,易使血管直径变窄、血流速度减慢,加速动脉粥样硬化进展。目前,关于寒邪导致脉痹的病因学理论尚未得到完全阐发,本文基于“寒中于暮”中“暮”的解释——“营”“岁暮”“日暮”“阳衰阴胜之时”,提出寒邪易伤营血而致脉痹的观点,并论述了寒邪伤脉的病机。从外环境来看,寒邪伤脉是有一定条件的,四季在冬,日在夜半;从内环境来看,寒邪伤脉可分为寒伤、寒郁、寒结3个阶段,在此过程中,阳气的强弱是寒邪致病与否的决定性因素。从“寒中于暮”探讨动脉粥样硬化的病因病机,为进一步阐明该病发病机理、拓展其临证治疗提供了新思路。
Atherosclerosis is classified as"vessel bi"in traditional Chinese medicine,and cold evil is one of its important causes.Cold,having the properties of coagulation,stagnation,and contraction,tends to narrow the diameter of blood vessels and slow down blood flow,which can promote the pathophysiological process of atherosclerosis.At present,the etiological theory of vessel bi caused by cold evil has not been fully elaborated.Based on the explanations of"evening"in"pathogenic cold affecting in the evening",such as"ying","end of year","end of day",and"time of yang decline and yin exuberance",this paper proposes the viewpoint that the cold evil tends to affect ying-blood and cause vessel bi,and discusses its pathogenesis.From the perspective of the external environment,cold evil affecting the vessel is conditional,often occurring in winter and in the middle of the night.From the perspective of internal environment,the cold evil affects the vessel in a process which can be manifested in three stages:cold injury,cold stagnation,and cold congelation.The strength of yang qi is the factor that determine whether the cold evil can cause disease.Exploring the etiology and pathogenesis of atherosclerosis from the perspective of"pathogenic cold affecting in the evening"provides a new idea for further elucidating the pathogenesis of the disease and expanding its clinical treatment.
作者
张晋锐
吴圣贤
杜雅薇
ZHANG Jinrui;WU Shengxian;DU Yawei(Dongzhimen Hospital,Beijing University of Chinese Medicine,Beijing 100700,China)
出处
《北京中医药大学学报》
CAS
CSCD
北大核心
2024年第1期92-96,共5页
Journal of Beijing University of Traditional Chinese Medicine
基金
国家自然科学基金项目(No.82174339)。
关键词
动脉粥样硬化
寒中于暮
寒邪
atherosclerosis
pathogenic cold affecting in the evening
cold evil
