摘要
目的探讨CT常规参数特征与CT纹理分析参数对于肺部可吸收性肺磨玻璃结节与肺腺癌的鉴别诊断价值。方法回顾性分析152例肺部磨玻璃结节的影像学资料。其中随访(3~6个月)或抗炎后吸收消失的65例为临床可吸收组,直接手术切除且病理为肺腺癌的87例为手术恶性组。通过分析软件得到肺结节CT常规参数及CT纹理分析参数;比较肺结节常规参数与CT纹理分析参数的组间差异;最后构建二元Logistic回归预测模型,比较两种模型之间的鉴别诊断效能。结果长径、短径、平均径、体积、实性部分占位、最大CT值、最小CT值、平均CT值、分叶征、毛刺征、胸膜凹陷征,在两组间差异具有统计学意义(P<0.05);CT纹理分析共计获得56个参数,其组间差异具有统计学意义(P<0.05);二元Logistic回归分析显示:最大CT值、分叶征、毛刺征、胸膜凹陷征、熵、正像素平均值、逆差距、表面积与体积比值,可作为独立预测因子,有助于鉴别肺部可吸收磨玻璃结节与肺腺癌结节。常规参数预测模型、CT纹理分析预测模型无明显鉴别诊断效能差异(P=0.542)。结论肺部磨玻璃结节的CT常规参数、CT纹理分析对肺部可吸收磨玻璃结节、肺腺癌的鉴别诊断具有一定价值。
Objective To investigate the diagnostic performance of conventional CT parameters and CT texture analysis parameters in differentiating absorbable pulmonary ground glass nodules from lung adenocarcinoma nodules.Methods Imaging data of 152 patients with pulmonary ground glass nodules in our hospital were analyzed retrospectively.Of these,65 patients were classified into clinically absorbable group,whose pulmonary nodules were disappeared in the followed 3-6 months or disappeared after anti-inflammatory treatment,and 87 patients were classified into malignant group,whose pulmo-nary nodules were resected by surgery,and a pathological examination confirmed the diagnosis of malignancy.Conventional CT parameters and CT texture analysis parameters of pulmonary nodules were obtained by analysis software.Difference in conventional parameters and CT texture analysis parameters between two groups were compared.Finally,two binary logistic regression prediction models were constructed to compare their efficacy of differential diagnosis for malignant pulmonary ground glass nodules.Results Long diameter,short diameter,average diameter,volume,solid part space occupying,maxi-mum CT value,minimum CT value,average CT value,lobulation sign,burr sign,pleural indentation sign were found to be significantly different between the two groups(P<0.05).A total of 56 variables obtained using CT texture analysis showed statistically significant between groups(P<0.05).Binary logistic regression analysis indicated that maximum CT value,lob-ulation sign,hair prick sign,pleural indentation sign,entropy,mean value of positive pixels,inverse difference,surface area to volume ratio could be used as independent predictors for differentiating between absorbable ground glass nodules and ma-lignant ground glass nodules.There was no significant difference between conventional parameter prediction model and CT texture analysis prediction model in discrimination performance(P=0.542).Conclusion Conventional CT parameters and CT texture analysis of pulmonary
作者
臧汉杰
朱建国
何雯雯
王之悦
李海歌
唐继来
ZANG Hanjie;ZHU Jianguo;HE Wenwen(Department of Radiology,the Second Affiliated Hospital of Nanjing Medical University,Nanjing 210011,P.R.China)
出处
《临床放射学杂志》
北大核心
2024年第1期47-51,共5页
Journal of Clinical Radiology
关键词
磨玻璃结节
计算机断层扫描
纹理分析
常规参数
鉴别诊断
Ground glass nodule
Computed tomography
Texture analysis
Conventional parameters
Differential diagnosis
