摘要
新型冠状病毒肺炎(coronavirus disease 2019,COVID-19)在全球范围内持续流行,严重威胁人类生命健康,开发有效治疗药物尤为重要.中和抗体作为一种特异性抗病毒治疗药物,药品研发和临床应用都取得较快进展,目前已有部分中和抗体获得紧急使用授权,应用于COVID-19患者的治疗.因此本文对中和抗体类新型冠状病毒治疗药物的临床应用及有效性、安全性进行综述,以期为临床用药提供参考.
The ongoing global epidemic of COVID-19 has exerted a serious impact on life quality of human.Therefore,the development of effective therapeutic agents is particularly important.As specific antiviral agents,neutralizing antibodies have been successfully applied on some viral infectious diseases.Currently,the development of neutralizing antibodies against SARS-CoV-2 is progressing rapidly,and several products have been authorized for emergency use.In this paper,the clinical application,efficacy and safety of SARS-CoV-2 neutralizing antibodies are reviewed,in order to provide reference for the clinical application of neutralizing antibodies.
作者
王璐
曾露
桂玲
魏安华
WANG Lu;ZENG Lu;GUI Ling;WEI An-hua(Department of Pharmacy,Tongji Hospital,Tongji Medical College,Huazhong University of Science&Technology,Wuhan 430030,China)
出处
《中国新药杂志》
CAS
CSCD
北大核心
2024年第2期131-137,共7页
Chinese Journal of New Drugs
