摘要
目的分析中性粒细胞弹性蛋白酶(neutrophil elastase,NE)、白细胞介素-6(interleukin-6,IL-6)及C-反应蛋白(C-reactive protein,CRP)与小儿细菌性肺炎危重程度的相关性,为小儿细菌性肺炎的诊治提供依据。方法选取2022年1—12月在冠县人民医院诊断为细菌性肺炎的120例患儿作为研究对象,按照《中国急诊重症肺炎临床实践专家共识》对“重症肺炎”诊断标准,分为A组:轻症组(80例),B组:重症组(40例)。对比两组的NE、IL-6及CRP水平,分析NE、IL-6及CRP与小儿肺炎严重程度的相关性。结果A组患儿NE、IL-6及CRP水平均低于B组,差异有统计学意义(P均<0.05)。NE、IL-6及CRP与小儿肺炎严重程度呈正相关(r=0.724、0.712、0.698,P均<0.05)。结论NE、IL-6及CRP与小儿肺炎严重程度呈正相关。
Objective To analyze the correlation between neutrophil elastase(NE),interleukin-6(IL-6)and C-reactive protein(CRP)and the severity of bacterial pneumonia in children,and to provide basis for diagnosis and treat⁃ment of bacterial pneumonia in children.Methods A total of 120 children diagnosed with bacterial pneumonia in Guanxian People's Hospital from January to December 2022 were selected as the study objects,and were divided into group A(mild case group)(80 cases)and group B(severe case group)(40 cases)according to the diagnostic criteria for"severe pneumonia"in China's Emergency Severe Pneumonia Clinical Practice Expert Consensus.The levels of NE,IL-6 and CRP in the two groups were compared to analyze the correlation between NE,IL-6 and CRP and the sever⁃ity of pneumonia in children.Results The levels of NE,IL-6 and CRP in group A were lower than those in group B,and the differences were statistically significant(all P<0.05).NE,IL-6 and CRP were positively correlated with the se⁃verity of pediatric pneumonia(r=0.724,0.712,0.698,all P<0.05).Conclusion NE,IL-6 and CRP were positively cor⁃related with the severity of pneumonia in children.
作者
姚丽
YAO Li(Department of Pediatrics,Guanxian County People's Hospital,Guanxian,Shandong Province,252500 China)
出处
《系统医学》
2023年第24期125-128,共4页
Systems Medicine
